Diagnostics for COVID-19: moving from pandemic response to control

RW Peeling, DL Heymann, YY Teo, PJ Garcia - The Lancet, 2022 - thelancet.com
Diagnostics have proven to be crucial to the COVID-19 pandemic response. There are three
major methods for the detection of SARS-CoV-2 infection and their role has evolved during …

COVID-19 vaccines: where we stand and challenges ahead

G Forni, A Mantovani - Cell Death & Differentiation, 2021 - nature.com
In the eleven months elapsed since the identification of the SARS-CoV-2 virus and its
genome, an exceptional effort by the scientific community has led to the development of over …

Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial

PB Gilbert, DC Montefiori, AB McDermott, Y Fong… - Science, 2022 - science.org
In the coronavirus efficacy (COVE) phase 3 clinical trial, vaccine recipients were assessed
for neutralizing and binding antibodies as correlates of risk for COVID-19 disease and as …

Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study

CH Hansen, D Michlmayr, SM Gubbels, K Mølbak… - The lancet, 2021 - thelancet.com
Background The degree to which infection with SARS-CoV-2 confers protection towards
subsequent reinfection is not well described. In 2020, as part of Denmark's extensive, free-of …

COVID-19 transmission, current treatment, and future therapeutic strategies

VS Salian, JA Wright, PT Vedell, S Nair… - Molecular …, 2021 - ACS Publications
At the stroke of the New Year 2020, COVID-19, a zoonotic disease that would turn into a
global pandemic, was identified in the Chinese city of Wuhan. Although unique in its …

Efficacy and safety of COVID-19 vaccines in older people

RL Soiza, C Scicluna, EC Thomson - Age and ageing, 2021 - academic.oup.com
Several vaccines against coronavirus disease 2019 (COVID-19) are on the cusp of
regulatory approval. Their safety and efficacy in older people is critical to their success. Even …

[HTML][HTML] SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants

D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …

Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

Safety and immunogenicity of S-Trimer (SCB-2019), a protein subunit vaccine candidate for COVID-19 in healthy adults: a phase 1, randomised, double-blind …

P Richmond, L Hatchuel, M Dong, B Ma, B Hu… - The lancet, 2021 - thelancet.com
Background As part of the accelerated development of vaccines against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), we report a dose-finding and adjuvant …

Immune evasion of SARS-CoV-2 emerging variants: what have we learnt so far?

I Lazarevic, V Pravica, D Miljanovic, M Cupic - Viruses, 2021 - mdpi.com
Despite the slow evolutionary rate of SARS-CoV-2 relative to other RNA viruses, its massive
and rapid transmission during the COVID-19 pandemic has enabled it to acquire significant …