Abstract Since December 2019 the Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) has produced an outbreak of pulmonary disease which has soon become a …

The outbreak of Covid-19 disease caused by SARS-CoV-19, along with the lack of targeted
medicaments and vaccines, forced the scientific world to search for new antiviral …

The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through
direct binding to host receptors including ACE2. An alternate entry receptor for the virus was …

We present a supercomputer-driven pipeline for in silico drug discovery using enhanced
sampling molecular dynamics (MD) and ensemble docking. Ensemble docking makes use …

In times of health crisis, including the current COVID‐19 pandemic, the potential benefit of
botanical drugs and supplements emerges as a focus of attention, although controversial …

Many countries have been affected by the worldwide outbreak of COVID‐19. Among
Western countries, Italy has been particularly hit at the beginning of the pandemic …

In spite of the successful use of monoclonal antibodies (mAbs) in clinic for tumor treatment,
their applications are still hampered in therapeutic development due to limitations, such as …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection continues to be a
serious global public health threat. The 3C-like protease (3CLpro) is a virus protease …

COVID-19 and its causative organism SARS-CoV2 that emerged from Wuhan city, China
have paralyzed the world. With no clinically approved drugs, the global health system is …

At the end of 2019, a life threatening viral infection (COVID-19) caused by a novel
coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was …