Role of respiratory syncytial virus in pediatric pneumonia

S Bianchini, E Silvestri, A Argentiero, V Fainardi, G Pisi… - Microorganisms, 2020 - mdpi.com
Respiratory viral infections represent the leading cause of hospitalization in infants and
young children worldwide and the second leading cause of infant mortality. Among these …

[HTML][HTML] Recurrent rhinovirus infections in a child with inherited MDA5 deficiency

IT Lamborn, H Jing, Y Zhang, SB Drutman… - Journal of Experimental …, 2017 - rupress.org
MDA5 is a cytosolic sensor of double-stranded RNA (ds) RNA including viral byproducts and
intermediates. We studied a child with life-threatening, recurrent respiratory tract infections …

[HTML][HTML] Macrolide-resistant Mycoplasma pneumoniae infections in pediatric community-acquired pneumonia

YC Chen, WY Hsu, TH Chang - Emerging infectious diseases, 2020 - ncbi.nlm.nih.gov
A high prevalence rate of macrolide-resistant Mycoplasma pneumoniae (MRMP) has been
reported in Asia. We performed a systematic review and meta-analysis to investigate the …

Predicting severe pneumonia outcomes in children

DJ Williams, Y Zhu, CG Grijalva, WH Self… - …, 2016 - publications.aap.org
BACKGROUND: Substantial morbidity and excessive care variation are seen with pediatric
pneumonia. Accurate risk-stratification tools to guide clinical decision-making are needed …

Procalcitonin accurately identifies hospitalized children with low risk of bacterial community-acquired pneumonia

C Stockmann, K Ampofo, J Killpack… - Journal of the …, 2018 - academic.oup.com
Background Lower procalcitonin (PCT) concentrations are associated with reduced risk of
bacterial community-acquired pneumonia (CAP) in adults, but data in children are limited …

Metabolomic analysis reveals potential biomarkers and the underlying pathogenesis involved in Mycoplasma pneumoniae pneumonia

J Li, LDW Luu, X Wang, XD Cui, X Huang… - Emerging microbes & …, 2022 - Taylor & Francis
Although previous studies have reported the use of metabolomics for infectious diseases,
little is known about the potential function of plasma metabolites in children infected with …

[HTML][HTML] Burden of pneumococcal disease due to serotypes covered by the 13-valent and new higher-valent pneumococcal conjugate vaccines in the United States

L Huang, M Wasserman, L Grant, R Farkouh, V Snow… - Vaccine, 2022 - Elsevier
The addition of pneumococcal conjugate vaccines (PCVs) to the United States (US) national
immunization program led to significant reductions in incidence, mortality, and associated …

Impact of routine childhood immunization in reducing vaccine-preventable diseases in the United States

SE Talbird, J Carrico, EM La, C Carias… - …, 2022 - publications.aap.org
BACKGROUND AND OBJECTIVES Current routine immunizations for children aged≤ 10
years in the United States in 2019 cover 14 vaccine-preventable diseases. We characterize …

Blood biomarkers differentiating viral versus bacterial pneumonia aetiology: a literature review

J Thomas, A Pociute, R Kevalas, M Malinauskas… - Italian journal of …, 2020 - Springer
Background and objectives The goal of this literature review is to compare current studies
regarding the accuracy of different serum markers in differentiating viral from bacterial …

Pneumonia as a cardiovascular disease

MI Restrepo, LF Reyes - Respirology, 2018 - Wiley Online Library
Community‐acquired pneumonia (CAP) is an important cause of death around the globe.
Up to 30% of patients admitted to hospital for CAP develop cardiovascular complications (ie …