[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Applications of chitosan-alginate-based nanoparticles—An up-to-date review

AG Niculescu, AM Grumezescu - Nanomaterials, 2022 - mdpi.com
Chitosan and alginate are two of the most studied natural polymers that have attracted
interest for multiple uses in their nano form. The biomedical field is one of the domains …

Sustainable biodegradable biopolymer-based nanoparticles for healthcare applications

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2023 - mdpi.com
Biopolymeric nanoparticles are gaining importance as nanocarriers for various biomedical
applications, enabling long-term and controlled release at the target site. Since they are …

Carbohydrate polymer-based bioadhesive formulations and their potentials for the treatment of ocular diseases: a review

X Tang, J Liu, R Yan, Q Peng - International Journal of Biological …, 2023 - Elsevier
Eyes are directly exposed to the outer environment and susceptible to infections, leading to
various ocular disorders. Local medication is preferred to treat eye diseases due to its …

Breaking barriers in eye treatment: Polymeric nano-based drug-delivery system for anterior segment diseases and glaucoma

KY Wu, S Ashkar, S Jain, M Marchand, SD Tran - Polymers, 2023 - mdpi.com
The eye has anatomical structures that function as robust static and dynamic barriers,
limiting the penetration, residence time, and bioavailability of medications administered …

[HTML][HTML] Recent progress in alginate-based carriers for ocular targeting of therapeutics

S Karmakar, S Manna, S Kabiraj, S Jana - Food Hydrocolloids for Health, 2022 - Elsevier
Eye is one of the susceptible organs of the human body which is associated with several
internal organs including the brain. Due to the protective mechanisms of body and ocular …

Xanthan and alginate-matrix used as transdermal delivery carrier for piroxicam and ketoconazole

A Dimofte, MV Dinu, N Anghel, F Doroftei… - International Journal of …, 2022 - Elsevier
This study presents new drug delivery systems based on xanthan, unmodified or modified by
esterification with oleic acid, and alginate for controlled release of bioactive substances with …

Overcoming Treatment Challenges in Posterior Segment Diseases with Biodegradable Nano-Based Drug Delivery Systems

KY Wu, M Joly-Chevrier, D Akbar, SD Tran - Pharmaceutics, 2023 - mdpi.com
Posterior segment eye diseases present a challenge in treatment due to the complex
structures in the eye that serve as robust static and dynamic barriers, limiting the penetration …

Experimental and multi‐scale finite element modeling for evaluating healing efficiency of electro‐sprayed microcapsule based glass fiber‐reinforced polymer …

H Dadras, R Barbaz‐Isfahani… - Polymer …, 2022 - Wiley Online Library
Microcapsule based glass fiber‐reinforced polymer (GFRP) composites have attracted
enormous attention due to enhancement of structures' longevity, reducing expenses, and …

Formulation and evaluation of paclitaxel-loaded boronated chitosan/alginate nanoparticles as a mucoadhesive system for localized cervical cancer drug delivery

OM Kolawole, AR Ifeanafor, WA Ifade… - Journal of Drug Delivery …, 2023 - Elsevier
Cervical cancer remains a significant global health challenge, and there is a need for
innovative drug delivery systems to improve the efficacy of anticancer drugs. In this study, we …