It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with
Alzheimer's disease (AD). Recently, we showed that abnormal levels of Aβ42 in …

Binding of programmed death ligand-1 (PD-L1) to programmed cell death protein-1 (PD1)
leads to cancer immune evasion via inhibition of T cell function. One of the defining …

Human episodic memory critically depends on subregions of the medial temporal lobe,
which are part of functional brain systems such as the anterior-temporal and the posterior …

For the past 25 years, the field of neuroimaging has witnessed the development of several
software packages for processing multi-parametric magnetic resonance imaging (mpMRI) to …

Modern scientific endeavors increasingly require team collaborations to construct and
interpret complex computational workflows. This work describes an image-analysis …

The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the
brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately …

In Alzheimer's disease, post-mortem studies have shown that the first cortical site where
neurofibrillary tangles appear is the transentorhinal region, a subregion within the medial …

Magnetic resonance imaging (MRI) is a flexible medical imaging modality that often lacks
reproducibility between protocols and scanners. It has been shown that even when care is …

What determines the cortical location at which a given functionally specific region will arise
in development? We tested the hypothesis that functionally specific regions develop in their …

Abstract The Advanced Normalizations Tools ecosystem, known as ANTsX, consists of
multiple open-source software libraries which house top-performing algorithms used …