With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

Hypoxia and inflammation are frequently co-incidental features of the tissue
microenvironment in a wide range of inflammatory diseases. While the impact of hypoxia on …

Metabolic enzymes have an indispensable role in metabolic reprogramming, and their
aberrant expression or activity has been associated with chemosensitivity. Hence, targeting …

Background Cancer cells selectively promote the translation of oncogenic transcripts to
stimulate cancer progression. Although growing evidence has revealed that tRNA …

Background: Cuproptosis is a new type of cell death that induces protein toxic stress and
eventually leads to cell death. Hence, regulating cuproptosis in tumor cells is a new …

Abstract Environmental Benzo (a) pyrene (BaP) and its ultimate metabolite BPDE (benzo (a)
pyrene-7, 8-dihydrodiol-9, 10-epoxide) are typical persistent organic pollutants and …

Intervertebral disc degeneration (IDD), an important cause of chronic low back pain (LBP), is
considered the pathological basis for various spinal degenerative diseases. A series of …

An updated LncTarD 2.0 database provides a comprehensive resource on key lncRNA–
target regulations, their influenced functions and lncRNA-mediated regulatory mechanisms …

Obesity has reached epidemic proportions globally. Although modern adoption of a
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …

Epigenetic modifications and metabolism are two fundamental biological processes. During
tumorigenesis and cancer development both epigenetic and metabolic alterations occur and …