M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …
Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …
P Surendran, ID Stewart, VPW Au Yeung, M Pietzner… - Nature Medicine, 2022 - nature.com
Garrod's concept of 'chemical individuality'has contributed to comprehension of the molecular origins of human diseases. Untargeted high-throughput metabolomic …
Reproductive longevity is essential for fertility and influences healthy ageing in women,, but insights into its underlying biological mechanisms and treatments to preserve it are limited …
Clinical laboratory tests are a critical component of the continuum of care. We evaluate the genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n …
RM Samuel, H Majd, MN Richter, Z Ghazizadeh… - Cell Stem Cell, 2020 - cell.com
SARS-CoV-2 infection has led to a global health crisis, and yet our understanding of the disease and potential treatment options remains limited. The infection occurs through …
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is associated with a substantially increased lifetime risk of comorbidities, including type 2 …
In this communication, we present arguments for androgen sensitivity as a likely determinant of COVID‐19 disease severity. The androgen sensitivity model explains why males are more …
P Moghetti, F Tosi - Journal of endocrinological investigation, 2021 - Springer
PCOS is a common and heterogeneous endocrine disorder in women of reproductive age, frequently associated with metabolic abnormalities. It was estimated that about 75% of these …