Early-life exposures to environmental insults can misprogram development and increase
metabolic disease risk in a sex-dependent manner by mechanisms that remain poorly …

Endometrial cancer is a common gynaecological cancer with increasing incidence and
mortality. In the last decade, endometrial cancer genome-wide association studies (GWAS) …

Importance Autism spectrum disorder (ASD) is associated with significant clinical,
neuroanatomical, and genetic heterogeneity that limits precision diagnostics and treatment …

Common uterine diseases include endometriosis, uterine fibroids, endometrial polyps,
endometrial hyperplasia, endometrial cancer, and endometrial dysfunction causing infertility …

Context Insulin resistance (IR) is associated with polycystic ovaries and hyperandrogenism,
but underpinning mechanisms are poorly understood and therapeutic options are limited …

Endometrial cancer (EC) is a common gynecological cancer. In some parts of the world, the
incidence and mortality of EC are on the rise. Understanding the risk factors of EC is …

Context Polycystic ovary syndrome (PCOS) is characterized by ovulatory dysfunction and
hyperandrogenism and can be associated with cardiometabolic dysfunction, but it remains …

This narrative review summarizes key points of the pathogenesis and diagnosis of the
ageing-related decline of testosterone (T) in men. The condition is commonly termed late …

Context Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, with disease loci
identified from genome-wide association studies (GWAS) having largely unknown …

Abstract Despite affecting~ 11–13% of women globally, polycystic ovary syndrome (PCOS)
is a substantially understudied condition. PCOS, possibly extending to men's health …