Trypanosomatid parasites and fungi cause highly prevalent diseases. Ergosterol plays a
crucial role in the structure and normal function of the membrane of these microorganisms. It …

Chagas' disease (American Trypanosomiasis) is an ancient and endemic illness in Latin
America caused by the protozoan parasite Trypanosoma cruzi. Although there is an urgent …

Malaria is one of the oldest and deadliest parasitic diseases globally, and it still poses a
global health issue today because of the emergence of new strains resistant to the first-line …

Human African trypanosomiasis (sleeping sickness) and leishmaniasis are prevalent
zoonotic diseases caused by genomically related trypanosomatid protozoan parasites …

Human African Trypanosomiasis (HAT) is a neglected tropical disease widespread in sub-
Saharan Africa. Rhodesain, a cysteine protease of Trypanosoma brucei rhodesiense, has …

Currently the only drug available to treat Chagas disease in Brazil is benznidazole (BZN).
Therefore, there is an urgent need to discover and develop new anti-Trypanosoma cruzi …

Searching for new prospective drugs against Chagas disease (American trypanosomiasis)
and Leishmaniasis, a series of five heteroleptic vanadium compounds,[VIVO (LH)(mpo)] …

A series of new transition metal coordination polymers,[Zn (Ac) 2 (FLZ) 2] n (1),[Zn (FLZ) 2
(Cl) 2] n (2),{[Zn (FLZ) 2](NO 3) 2} n (3),[Cu (FLZ) 2 (CH₃COO) 4] n (4),{[Cu (FLZ) 2 Cl 2]} n …

Human African trypanosomiasis (HAT, sleeping sickness) and American trypanosomiasis
(Chagas disease) are endemic zoonotic diseases caused by genomically related …

Current treatment for Chagas' disease is based on two drugs, Nifurtimox and Benznidazol,
which have limitations that reduce the effectiveness and continuity of treatment. Thus, there …