[HTML][HTML] New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis

T Yuan, T Yang, H Chen, D Fu, Y Hu, J Wang, Q Yuan… - Redox biology, 2019 - Elsevier
Oxidative stress and inflammation interact in the development of diabetic atherosclerosis.
Intracellular hyperglycemia promotes production of mitochondrial reactive oxygen species …

Physiological and pathological roles of aldose reductase

M Singh, A Kapoor, A Bhatnagar - Metabolites, 2021 - mdpi.com
Aldose reductase (AR) is an aldo-keto reductase that catalyzes the first step in the polyol
pathway which converts glucose to sorbitol. Under normal glucose homeostasis the pathway …

Can metformin exert as an active drug on endothelial dysfunction in diabetic subjects?

T Salvatore, PC Pafundi, R Galiero, L Rinaldi… - Biomedicines, 2020 - mdpi.com
Cardiovascular mortality is a major cause of death among in type 2 diabetes (T2DM).
Endothelial dysfunction (ED) is a well-known important risk factor for the development of …

Initiating pollen sensitization–complex source, complex mechanisms

L Pointner, A Bethanis, M Thaler… - Clinical and translational …, 2020 - Springer
The mechanisms involved in the induction of allergic sensitization by pollen are not fully
understood. Within the last few decades, findings from epidemiological and experimental …

Psoriatic resolved skin epidermal keratinocytes retain disease-residual transcriptomic and epigenomic profiles

A Ghaffarinia, F Ayaydin, S Póliska… - International Journal of …, 2023 - mdpi.com
The disease-residual transcriptomic profile (DRTP) within psoriatic healed/resolved skin and
epidermal tissue-resident memory T (TRM) cells have been proposed to be crucial for the …

Aldose reductase inhibitor engeletin suppresses pelvic inflammatory disease by blocking the phospholipase C/protein kinase C-dependent/NF-κB and MAPK …

C Wang, L La, H Feng, Q Yang, F Wu… - Journal of Agricultural …, 2020 - ACS Publications
Pelvic inflammatory disease (PID) is a common inflammation in the upper reproductive tract
in women and may cause serious and costly consequences without effective treatment …

[PDF][PDF] Effects of daily consumption of probiotic yoghurt on inflammatory factors in pregnant women: a randomized controlled trial

Z Asemi, S Jazayeri, M Najafi, M Samimi… - Pakistan Journal of …, 2011 - researchgate.net
Previous studies have shown that inflammatory factors increases in pregnancy and is
associated with several complications of pregnancy. The aim of this study was to assess …

[图书][B] Aldose reductase inhibitors as potential therapeutic drugs of diabetic complications

C Zhu - 2013 - books.google.com
Diabetes mellitus has become a major health threat as a global rise in it has been seen. The
chronic disease has afflicted over 171 million people worldwide in 2000 and the incidence is …

Geniposide inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma

Y Deng, M Guan, X Xie, X Yang, H Xiang, H Li… - International …, 2013 - Elsevier
Our group recently reported the strong anti-inflammatory effects of geniposide (Gen), a
bioactive iridoid glucoside derived from gardenia jasminoides, in a mouse acute lung injury …

Detoxifying enzymes at the cross-roads of inflammation, oxidative stress, and drug hypersensitivity: role of glutathione transferase P1-1 and aldose reductase

FJ Sanchez-Gomez, B Diez-Dacal… - Frontiers in …, 2016 - frontiersin.org
Phase I and II enzymes are involved in the metabolism of endogenous reactive compounds
as well as xenobiotics, including toxicants and drugs. Genotyping studies have established …