Machine learning (ML) is increasingly used in clinical oncology to diagnose cancers, predict
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …

Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to
revolutionize precision oncology and blood-based cancer screening. Recent technological …

Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …

Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

A system for programmable export of RNA molecules from living cells would enable both
non-destructive monitoring of cell dynamics and engineering of cells capable of delivering …

The ability to use blood to predict the outcomes of Parkinson's disease, including disease
progression and cognitive and motor complications, would be of significant clinical value …

Microgravity is associated with immunological dysfunction, though the mechanisms are
poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear …

Liquid biopsies provide a means for the profiling of cell-free RNAs secreted by cells
throughout the body. Although well-annotated coding and non-coding transcripts in blood …

This review delves into the rapidly evolving landscape of liquid biopsy technologies based
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …

The analysis of biomarkers in biological fluids, also known as liquid biopsies, is seen with
great potential to diagnose complex diseases such as cancer with a high sensitivity and …