Aspiring toward equitable benefits from genomic advances to individuals of ancestrally diverse backgrounds

Y Wang, Y He, Y Shi, DC Qian, KJ Gray, R Winn… - The American Journal of …, 2024 - cell.com
Advancements in genomic technologies have shown remarkable promise for improving
health trajectories. The Human Genome Project has catalyzed the integration of genomic …

[HTML][HTML] The Role of Nutrition in the Development and Management of Chronic Obstructive Pulmonary Disease

A Heefner, T Simovic, K Mize, P Rodriguez-Miguelez - Nutrients, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a prevalent lung condition associated
with significant morbidity and mortality. The management of COPD classically involves …

[HTML][HTML] Decoding Genetics, Ancestry, and Geospatial Context for Precision Health

S Koyama, Y Wang, K Paruchuri, MM Uddin, SMJ Cho… - medRxiv, 2023 - ncbi.nlm.nih.gov
Abstract Mass General Brigham, an integrated healthcare system based in the Greater
Boston area of Massachusetts, annually serves 1.5 million patients. We established the …

[HTML][HTML] Circular RNAs: emerging players in asthma and COPD

X Liu, MK Ali, K Dua, Y Mao, J Liu - Frontiers in Cell and …, 2023 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) belong to a unique class of endogenously expressed non-protein-
coding RNAs with a distinct circularized structure, characterized by the absence of 5′-cap …

Body mass index, smoking behavior, and depression mediated the effects of schizophrenia on chronic obstructive pulmonary disease: trans-ethnic Mendelian …

Y Ni, DW Zhang, W Tang, L Xiang, X Cheng… - Frontiers in …, 2024 - frontiersin.org
Background Previous studies have highlighted the association between schizophrenia
(SCZ) and chronic obstructive pulmonary disease (COPD), yet the causal relationship …

Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs)

MK Chung, JS House, FS Akhtari, KC Makris… - …, 2024 - academic.oup.com
This paper explores the exposome concept and its role in elucidating the interplay between
environmental exposures and human health. We introduce two key concepts critical for …

[HTML][HTML] Comparative analysis between PUMA and CAPTURE questionnaires for chronic obstructive pulmonary disease (COPD) screening in smokers

RRB Sebayang, P Pandia, A Pradana, AP Tarigan… - Narra J, 2024 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) presents a significant global challenge,
impacting health systems, economies, and societies. Its prevalence is anticipated to rise …

[PDF][PDF] Chronic obstructive pulmonary disease: Signs and symptoms, diagnosis, treatments, lifestyle risk factors and management

SY Lim, V Ulaganathan, B Gunasekaran, S Salvamani… - researchgate.net
ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is associated with increased
health complications, leading to a rise in mortality rates. COPD remains a significant global …