The universal effects of low-dose interleukin-2 across 13 autoimmune diseases in a basket clinical trial

R Lorenzon, C Ribet, F Pitoiset, S Aractingi… - Journal of …, 2024 - Elsevier
Background A Tregs insufficiency is central to autoimmune and inflammatory diseases
pathophysiology and low dose interleukin-2 (IL-2 LD) can specifically activate Tregs …

The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models

Z Wang, Z Liu, J Zheng, L Huang, R Jin, X Wang… - BMC …, 2024 - Springer
Background/aims Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease. The
imbalance of Th17/Treg cells has been reported in PBC patients. Low-dose IL-2 can …

[HTML][HTML] Rheumatoid arthritis: a complex tale of autoimmune hypersensitivity

J Heo, S Heo, JR Kang, J Kweon… - Exploration of …, 2024 - explorationpub.com
Rheumatoid arthritis (RA) is a complex autoimmune disorder characterized by a spectrum of
hypersensitivity reactions, encompassing Type II, Type III, and Type IV responses. Firstly, RA …