[HTML][HTML] Dysregulated expression and functions of microRNA-330 in cancers: A potential therapeutic target

A Jafarzadeh, MH Paknahad, M Nemati… - Biomedicine & …, 2022 - Elsevier
As small non-coding RNAs, MicroRNAs (miRNAs) bind to the 3′ untranslated region (3′-
UTR) of mRNA targets to control gene transcription and translation. The gene of miR-330 …

[HTML][HTML] Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition

S Guo, L Zhang, Y Zhang, Z Wu, D He, X Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Long non-coding RNA taurine up-regulated gene 1 (TUG1) emerges as new players in gene
regulation in several cancers; however, its mechanism of action in non-small cell lung …

[HTML][HTML] Combination strategies using EGFR-TKi in NSCLC therapy: learning from the gap between pre-clinical results and clinical outcomes

Z Yang, KY Tam - International journal of biological sciences, 2018 - ncbi.nlm.nih.gov
Although epidermal growth factor receptor (EGFR) inhibitors have been used to treat non-
small cell lung cancer (NSCLC) for decades with great success in patients with EGFR …

PTEN/AKT/mTOR signaling mediates anticancer effects of epigallocatechin‑3‑gallate in ovarian cancer

J Qin, M Fu, J Wang, F Huang, H Liu… - Oncology …, 2020 - spandidos-publications.com
Abstract Epigallocatechin‑3‑gallate (EGCG), a polyphenol present in green tea, exhibits
anticancer effects in various types of cancer. A number of studies have focused on the …

Long non‑coding RNA MEG3 inhibits cell migration and invasion of non‑small cell lung cancer cells by regulating the miR‑21‑5p/PTEN axis

D Lv, Q Bi, Y Li, J Deng, N Wu… - Molecular medicine …, 2021 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) are involved in the occurrence and progression of
numerous types of cancer. The aim of the present study was to evaluate the effect of the …

Lnc-GAN1 expression is associated with good survival and suppresses tumor progression by sponging mir-26a-5p to activate PTEN signaling in non-small cell lung …

RQ Wang, XR Long, NN Zhou, DN Chen… - Journal of Experimental …, 2021 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) play vital roles in the development
and progression of non-small-cell lung cancer (NSCLC); however, the role of most lncRNAs …

Hsa_circ_CSPP1/MiR-361-5p/ITGB1 Regulates Proliferation and Migration of Cervical Cancer (CC) by Modulating the PI3K-Akt Signaling Pathway

W Yang, T Xie - Reproductive Sciences, 2020 - Springer
This study aimed to investigate the regulatory mechanism of circular RNA CSPP1
(hsa_circ_CSPP1) in cervical cancer. Based on GEO database, differentially expressed …

[HTML][HTML] Long noncoding RNA FAL1 promotes cell proliferation, invasion and epithelial-mesenchymal transition through the PTEN/AKT signaling axis in non-small cell …

C Pan, G Yao, B Liu, T Ma, Y Xia, K Wei… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Recently, long non-coding RNAs (lncRNAs) have been found to have
many biological effects in different cancer stages. Several studies have revealed that focally …

Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR …

JH Chang, CW Cheng, YC Yang, WS Chen… - Journal of Experimental …, 2018 - Springer
Background Metastasis rather than the primary cancer determines the survival of cancer
patients. Activation of Akt plays a critical role in the epithelial-to-mesenchymal transition …

The circ-PITX1 promotes non-small cell lung cancer development via the miR-30e-5p/ITGA6 axis

W Li, P Yang, C Zhong, X Shen, X Shi, X Li - Cell Cycle, 2022 - Taylor & Francis
Non-small cell lung cancer (NSCLC) is one of the most prevalent tumors with high incidence
and mortality across the globe. Recently, increasing studies have demonstrated that circular …