Biomarkers of bipolar disorder based on metabolomics: A systematic review

J Chen, N Amdanee, X Zuo, Y Wang, M Gong… - Journal of Affective …, 2024 - Elsevier
Bipolar disorder (BD) is a severe affective disorder characterized by recurrent episodes of
depression or mania/hypomania, which significantly impair cognitive function, life skills, and …

The association between serum methylmalonic acid, cobalamin-related biomarkers, and long-term mortality risk in cancer survivors: a prospective cohort study

Y Liu, Z Huang, H Qiu, F Tang, F Liu, Y Zhang… - The American Journal of …, 2024 - Elsevier
Background Elevated serum methylmalonic acid (MMA), a marker of cobalamin (vitamin
B12) deficiency, has been linked to cancer progression. However, the impact of MMA or …

The association between methylmalonic acid, a biomarker of mitochondria dysfunction, and phenotypic age acceleration: A population-based study

B Cao, Y Xue, D Liu - Archives of gerontology and geriatrics, 2024 - Elsevier
Phenotypic age acceleration (PAA) is a sensitive marker of biological aging. Circulating
methylmalonic acid (MMA) is a novel biomarker of mitochondrial dysfunction and has been …

Increased serum methylmalonic acid levels were associated with the presence of cardiovascular diseases

X Wang, W Li, M Xiang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Background Functional vitamin B12 deficiency is common in cardiovascular diseases
(CVDs), such as heart failure and myocardial infarction. Methylmalonic acid (MMA) is a …

Associations of methylmalonic acid and depressive symptoms with mortality: a population-based study

B Cao, Y Xiao, D Liu - Translational Psychiatry, 2024 - nature.com
Methylmalonic acid (MMA), a biomarker of mitochondrial dysfunction, has been reported to
be associated with depression in specific populations (ie, older adults and postpartum …

Enhancing the biomass and docosahexaenoic acid‐rich lipid accumulation of Schizochytrium sp. in propionate wastewater

W Ma, X Li, F Zhang, ZY Zhang, WQ Yang… - Biotechnology …, 2023 - Wiley Online Library
In order to find a more effective way to obtain docosahexaenoic acid (DHA) rich lipid from
Schizochytrium sp., a widespread propionate wastewater (PW) is used. PW is a common …

Methylmalonic acid levels in serum, exosomes, and urine and its association with cblC type methylmalonic acidemia-induced cognitive impairment

S Sun, H Jin, Y Rong, W Song, Q Li - Frontiers in Neurology, 2022 - frontiersin.org
Background The cblC type methylmalonic acidemia is the most common methylmalonic
acidemia (MMA) in China. The biochemical characteristics of this disease include elevated …

Sexual dimorphism in mitochondrial dysfunction and diabetes mellitus: evidence from a population-based cohort study

S Wang, JC Guo, X Liu, W Tian, Y Zhang… - Diabetology & Metabolic …, 2023 - Springer
Background Pathophysiological mechanisms underlying sex-based differences in diabetes
remain poorly understood. Mitochondrial metabolite methylmalonic acid (MMA) …

On the Relationship between MMA Levels in Blood Products and Donor Sex, Age, and Donation Frequency

F Li, A Zhu, C Huang, H Guo, L Zhu… - Journal of Nutritional …, 2024 - jstage.jst.go.jp
As the aging process accelerates, the age structure of blood donors turns to older and even
aged groups. Methylmalonic acid (MMA), a byproduct of propionate metabolism, may be …

Propionic Acidemia, Methylmalonic Acidemia, and cblC Defect: Comparison of Untargeted Metabolomic Profiles

A Sidorina, G Catesini, E Sacchetti, C Rizzo… - 2024 - preprints.org
Methylmalonic acidemia (MMA), propionic acidemia (PA), and cobalamin C deficiency
(cblC) share a defect in propionic acid metabolism. In addition, cblC is also involved in the …