Co-delivery of isotretinoin and clindamycin by phospholipid-based mixed micellar system confers synergistic effect for treatment of acne vulgaris

G Sharma, Y Yachha, K Thakur, A Mahajan… - Expert Opinion on …, 2021 - Taylor & Francis
Background The combination therapy of Isotretinoin (ITR) and antibacterial formulations
administered through topical route suffer from several limitations including reduced …

Efficacy and safety of low-level light therapy by delicate pulsed light combined with low-dose oral isotretinoin for the treatment of acne vulgaris: a randomized split-face …

Y Li, J Xia, Y Zhu, S He, J Liu, W Zeng… - Lasers in Medical Science, 2022 - Springer
Acne vulgaris (AV) is a common dermatosis that causes psychological problems. Isotretinoin
is the first-line treatment for moderate-to-severe AV, but its onset of effect is delayed …

Advances in the Pathogenesis and Treatment of Rosacea: A Phenotype-Based Therapeutic Approach

G Galluccio, M D'Onghia, D Malvaso, L Lazzeri… - Cosmetics, 2024 - mdpi.com
Rosacea is a common chronic inflammatory skin disorder that mainly affects the central face.
It is primarily characterized by recurrent episodes of flushing, persistent erythema …

A prospective, randomized, split‐face study of concomitant administration of low‐dose oral isotretinoin with 30% salicylic acid chemical peeling for the treatment of …

D Ye, H Xue, S Huang, S He, Y Li, J Liu, Z Wang… - 2022 - Wiley Online Library
Background Acne vulgaris (AV) is a common dermatosis. For moderate to severe AV,
isotretinoin is the first‐line treatment. Chemical peeling with supramolecular salicylic acid …

[HTML][HTML] Isotretinoin self-nano-emulsifying drug delivery system: Preparation, optimization and antibacterial evaluation

R Alfaraj, S Hababah, EK Eltayb, FY Alqahtani… - Saudi Pharmaceutical …, 2024 - Elsevier
Purpose Isotretinoin (ITN) is a poorly water-soluble drug. The objective of this study was to
design a successful liquid self-nanoemulsifying drug delivery system (L-SNEDDS) for ITN to …

Isotretinoin: An updated review on the profile of its side-effects and the management

R Kandhari - Egyptian Journal of Dermatology and Venerology, 2023 - journals.lww.com
Acne vulgaris is a chronic inflammatory disorder of the skin, which presents as comedones,
papules, pustules, nodules, and cysts. Based on the multifactorial pathogenesis, a range of …

Isotretinoin and Thalidomide Down-Regulate c-MYC Gene Expression and Modify Proteins Associated with Cancer in Hepatic Cells

PN Ramírez-Flores, PJ Barraza-Reyna… - Molecules, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common form of liver cancer. The number of
cases is increasing and the trend for the next few years is not encouraging. HCC is usually …

[HTML][HTML] Isotretinoin Use and Liver Enzymes Changes: A Single-Center Study in Saudi Arabia

M Al Dhafiri, F Kaliyadan, S Almukhaimar, F Alsultan… - Cureus, 2023 - ncbi.nlm.nih.gov
Methods This study was a retrospective analysis that reviewed the medical data of 97
patients with acne at the King Faisal University Polyclinic who were taking systemic …

[HTML][HTML] Successful treatment of ivermectin refractory demodicosis with isotretinoin and permethrin cream

A Paichitrojjana, A Paichitrojjana - JAAD Case Reports, 2022 - Elsevier
Discussion Rosacea and rosacea-like demodicosis have many similarities. It is still
controversial in the literature that erythematotelangiectatic rosacea possibly corresponds to …

[HTML][HTML] A Case Report of Sebaceous Filaments

JP Mineroff, JT Hyde, S Hsu - Cureus, 2023 - ncbi.nlm.nih.gov
This report details a case of a 16-year-old African American girl who presented with a two-
year history of white spicules on her face without associated symptoms, including pruritus or …