[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

Two years into the COVID-19 pandemic: lessons learned

SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

[HTML][HTML] SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

CJ Neufeldt, B Cerikan, M Cortese, J Frankish… - Communications …, 2022 - nature.com
SARS-CoV-2 is a novel virus that has rapidly spread, causing a global pandemic. In the
majority of infected patients, SARS-CoV-2 leads to mild disease; however, in a significant …

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …

[HTML][HTML] Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal Transduction and Targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

[HTML][HTML] COVID-19 and the role of cytokines in this disease

A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …

COVID-19: inflammatory profile

Y Wang, S Perlman - Annual review of medicine, 2022 - annualreviews.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …

[HTML][HTML] The role of oxidative stress in the pathogenesis of infections with coronaviruses

C Gain, S Song, T Angtuaco, S Satta… - Frontiers in …, 2023 - frontiersin.org
Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19

A Attiq, LJ Yao, S Afzal, MA Khan - International immunopharmacology, 2021 - Elsevier
Abstract The coronavirus disease (COVID-19) has once again reminded us of the
significance of host immune response and consequential havocs of the immune …

Classic Signaling Pathways in Alveolar Injury and Repair Involved in Sepsis‐Induced ALI/ARDS: New Research Progress and Prospect

W Li, D Li, Y Chen, H Abudou, H Wang, J Cai… - Disease …, 2022 - Wiley Online Library
Sepsis is a common critical clinical disease with high mortality that can cause approximately
10 million deaths worldwide each year. Acute lung injury (ALI) or acute respiratory distress …