Single-nucleus assay for transposase-accessible chromatin using sequencing (snATAC-
seq) creates new opportunities to dissect cell type–specific mechanisms of complex …

The Metabolic Syndrome in Men (METSIM) study is a population-based study including
10,197 Finnish men examined in 2005–2010. The aim of the study is to investigate …

We report a genome-wide association scan in> 6,000 Latin Americans for pigmentation of
skin and eyes. We found eighteen signals of association at twelve genomic regions. These …

Background Diabetes mellitus (DM) is a major public health problem which prevalence is
constantly raising, particularly in low-and middle-income countries. Both diabetes mellitus …

Background Single nucleotide polymorphism (SNP) arrays for domestic cattle have
catalyzed the identification of genetic markers associated with complex traits for inclusion in …

Diabetes mellitus is a major risk factor for coronary heart disease (CHD). The major form of
diabetes mellitus is type 2 diabetes mellitus (T2D), which is thus largely responsible for the …

The genetic contribution to the variation in human lifespan is∼ 25%. Despite the large
number of identified disease-susceptibility loci, it is not known which loci influence …

Genome-wide association studies have implicated around 250 genomic regions in
predisposition to type 2 diabetes, with evidence for causal variants and genes emerging for …

Comparing transcript levels between healthy and diseased individuals allows the
identification of differentially expressed genes, which may be causes, consequences or …

The Mergeomics web server is a flexible online tool for multi-omics data integration to derive
biological pathways, networks, and key drivers important to disease pathogenesis and is …