The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

Organismal aging is inherently connected to the aging of its constituent cells and systems.
Reducing the biological age of the organism may be assisted by reducing the age of its cells …

Age-related changes in DNA methylation (DNAm) form the basis of the most robust
predictors of age—epigenetic clocks—but a clear mechanistic understanding of exactly …

Motivation Aging is intricately linked to diseases and mortality. It is reflected in molecular
changes across various tissues which can be leveraged for the development of biomarkers …

It has been four years since long COVID—the protracted consequences that survivors of
COVID-19 face—was first described. Yet, this entity continues to devastate the quality of life …

The prevalence of thyroid dysfunction diseases (TDFDs) and osteoporosis (OP) is high.
Previous studies have indicated a potential association between TDFDs and OP, yet the …

Aging is a complex and time-dependent decline in physiological function that affects most
organisms, leading to increased risk of age-related diseases. Investigating the molecular …

Aim: This is a brief description of links between nine epigenetic clocks related to human
aging and socioeconomic and behavioral characteristics as well as health outcomes …

The Hippo signalling pathway is a conserved kinase cascade that orchestrates diverse
cellular processes, such as proliferation, apoptosis, lineage commitment and stemness. With …

Identifying and validating biomarkers of aging is pivotal for understanding the aging process
and testing longevity interventions. Despite the development of numerous aging biomarkers …