Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rapalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

Immunogenic and reactogenic efficacy of Covaxin and Covishield: a comparative review

S Das, SS Kar, S Samanta, J Banerjee, B Giri… - Immunologic …, 2022 - Springer
SARS-CoV-2 is an RNA virus that was identified for the first time in December 2019 in
Wuhan, China. The World Health Organization (WHO) labeled the novel coronavirus …

Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

SARS‐CoV‐2 NSP8 suppresses type I and III IFN responses by modulating the RIG‐I/MDA5, TRIF, and STING signaling pathways

J Deng, SN Zheng, Y Xiao, ML Nan… - Journal of Medical …, 2023 - Wiley Online Library
SARS‐CoV‐2 has developed a variety of approaches to counteract host innate antiviral
immunity to facilitate its infection, replication and pathogenesis, but the molecular …

SARS‐CoV‐2 NSP7 inhibits type I and III IFN production by targeting the RIG‐I/MDA5, TRIF, and STING signaling pathways

J Deng, Y Zheng, SN Zheng, ML Nan… - Journal of Medical …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a poor inducer of innate
antiviral immunity, and the underlying mechanism still needs further investigation. Here, we …

Developing a multiepitope vaccine for the prevention of SARS-CoV-2 and monkeypox virus co-infection: A reverse vaccinology analysis

F Jiang, Y Liu, Y Xue, P Cheng, J Wang, J Lian… - International …, 2023 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and
monkeypox virus (MPXV) severely threaten human health; however, currently, no vaccine …

Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases

A Selvapandiyan, N Puri, P Kumar… - FEMS Microbiology …, 2023 - academic.oup.com
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …

[HTML][HTML] Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

[HTML][HTML] SARS-Cov2 acute and post-active infection in the context of autoimmune and chronic inflammatory diseases

R Larionova, K Byvaltsev, О Kravtsova, E Takha… - Journal of Translational …, 2022 - Elsevier
The clinical and immunological spectrum of acute and post-active COVID-19 syndrome
overlaps with criteria used to characterize autoimmune diseases such as rheumatoid …

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID‐19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
Innate and acquired immunity responses are crucial for viral infection elimination. However,
genetic variations in coding genes may exacerbate the inflammation or initiate devastating …