[HTML][HTML] Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

[HTML][HTML] Immunogenic and reactogenic efficacy of Covaxin and Covishield: a comparative review

S Das, SS Kar, S Samanta, J Banerjee, B Giri… - Immunologic …, 2022 - Springer
SARS-CoV-2 is an RNA virus that was identified for the first time in December 2019 in
Wuhan, China. The World Health Organization (WHO) labeled the novel coronavirus …

[HTML][HTML] Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

[HTML][HTML] NF-κB in biology and targeted therapy: new insights and translational implications

Q Guo, Y Jin, X Chen, X Ye, X Shen, M Lin… - … and Targeted Therapy, 2024 - nature.com
NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID‐19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
Innate and acquired immunity responses are crucial for viral infection elimination. However,
genetic variations in coding genes may exacerbate the inflammation or initiate devastating …

[HTML][HTML] The relationship between chronic immune response and neurodegenerative damage in long COVID-19

JP Elizalde-Díaz, CL Miranda-Narváez… - Frontiers in …, 2022 - frontiersin.org
In the past two years, the world has faced the pandemic caused by the severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2), which by August of 2022 has infected …

[HTML][HTML] Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

Developing a multiepitope vaccine for the prevention of SARS-CoV-2 and monkeypox virus co-infection: a reverse vaccinology analysis

F Jiang, Y Liu, Y Xue, P Cheng, J Wang, J Lian… - International …, 2023 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and
monkeypox virus (MPXV) severely threaten human health; however, currently, no vaccine …

[HTML][HTML] Activation of TLR4 by viral glycoproteins: A double-edged sword?

EA Halajian, EV LeBlanc, K Gee… - Frontiers in Microbiology, 2022 - frontiersin.org
Recognition of viral infection by pattern recognition receptors is paramount for a successful
immune response to viral infection. However, an unbalanced proinflammatory response can …

[HTML][HTML] Toll-like receptor signaling in severe acute respiratory syndrome coronavirus 2-induced innate immune responses and the potential application value of toll …

J Dai, Y Wang, H Wang, Z Gao, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Toll-like receptors (TLRs) are key sensors that recognize the pathogen-associated
molecular patterns (PAMPs) of severe acute respiratory syndrome coronavirus 2 (SARS …