Celecoxib microparticles for inhalation in COVID-19-related acute respiratory distress syndrome

MC Villa-Hermosilla, S Negro, E Barcia, C Hurtado… - Pharmaceutics, 2022 - mdpi.com
Inhalation therapy is gaining increasing attention for the delivery of drugs destined to treat
respiratory disorders associated with cytokine storms, such as COVID-19. The pathogenesis …

[HTML][HTML] Ultradiluted SARS-CoV-2 Spike Protein mitigates hyperinflammation in lung via ferritin and MMP-9 regulation in BALB/c mice

A Roy, A Sarkar, D Nayak, S Das - Virus Research, 2023 - Elsevier
Aim This study investigated the prophylactic and therapeutic role of ultradiluted preparation
of the Delta variant of SARS-CoV-2 recombinant spike (S) protein during S antigen-induced …

Enhancement of IL-6 production induced by SARS-CoV-2 Nucleocapsid protein and Bangladeshi COVID-19 patients' sera

A Hasan, R Rahim, EE Nakayama, K Uno, N Hasan… - Viruses, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by severe
acute respiratory syndrome coronavirus 2 that can have detrimental effects on multiple …

Farnesoid X receptor enhances epithelial ACE2 expression and inhibits virally induced IL-6 secretion: implications for intestinal symptoms of SARS-CoV-2

JS Smyth, JK Truong, A Rao, R Lin… - American Journal …, 2023 - journals.physiology.org
Intestinal inflammation and diarrhea are often associated with SARS-CoV-2 infection. The
angiotensin converting enzyme 2 (ACE2) receptor plays a key role in SARS-CoV-2 …

Efficacies of S-nitrosoglutathione (GSNO) and GSNO reductase inhibitor in SARS-CoV-2 spike protein induced acute lung disease in mice

J Kim, F Qiao, AK Singh, J Won, I Singh - Frontiers in Pharmacology, 2023 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which initially
surfaced in late 2019, often triggers severe pulmonary complications, encompassing various …

Antiviral, anti-inflammatory and antioxidant effects of curcumin and curcuminoids in SH-SY5Y cells infected by SARS-CoV-2

T Nicoliche, CS Bartolomeo, RMR Lemes… - Scientific Reports, 2024 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, affects neuronal cells, causing several
symptoms such as memory loss, anosmia and brain inflammation. Curcuminoids (Me08 e …

Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators

N Yasmeen, H Selvaraj, SS Lakhawat, M Datta… - Biochemical …, 2023 - Elsevier
Abstract Fatal “cytokine storms (CS)” observed in critically ill COVID-19 patients are
consequences of dysregulated host immune system and over-exuberant inflammatory …

The Effects of Fermented Feed on the Growth Performance, Antioxidant Activity, Immune Function, Intestinal Digestive Enzyme Activity, Morphology, and Microflora of …

F Xu, H Wu, J Xie, T Zeng, L Hao, W Xu, L Lu - Animals, 2023 - mdpi.com
Simple Summary The chicken digestive system is not fully developed, and the feed type and
shape have essential effects on it. The growth performance and health status would be …

Genome-wide gene expression analysis reveals unique genes signatures of epithelial reorganization in primary airway epithelium induced by type-I,-II and-III …

A Erb, UM Zissler, M Oelsner, AM Chaker… - Biosensors, 2022 - mdpi.com
Biosensors such as toll-like receptors (TLR) induce the expression of interferons (IFNs) after
viral infection that are critical to the first step in cell-intrinsic host defense mechanisms. Their …

[HTML][HTML] Probiotics for immunomodulation in prevention against respiratory viral infections with special emphasis on COVID-19

T Amrouche, ML Chikindas - AIMS microbiology, 2022 - ncbi.nlm.nih.gov
COVID-19 pandemic is currently causing high mortality and economic crisis, and several
drugs-based therapeutic strategies and vaccines are unfortunately used with little efficiency …