Abstract Large (> 100 kb), rare (< 1% in the population) copy number variants (CNVs) have
been shown to confer risk for schizophrenia (SZ), but the findings for bipolar disorder (BD) …

Objectives Bipolar disorder (BPD) shares genetic components with other psychiatric
disorders; however, uncertainty remains about where in the psychiatric spectra BPD falls. To …

Objectives To systematically review findings of GWAS in schizophrenia (SZ) and in bipolar
disorder (BD); and to interpret findings, with a focus on identifying independent replications …

The postsynaptic density (PSD) contains a complex set of proteins of known relevance to
neuropsychiatric disorders, and schizophrenia specifically. We enriched for this anatomical …

The 16p11. 2 600 kb BP4-BP5 deletion and duplication syndromes have been associated
with developmental delay; autism spectrum disorders; and reciprocal effects on the body …

Although the etiology of schizophrenia (SZ) remains unknown, it is increasingly clear that
immune dysregulation plays a central role. Genome-wide association studies reproducibly …

Summary Chromosome 16p11. 2 reciprocal genomic disorder, resulting from recurrent copy-
number variants (CNVs), involves intellectual disability, autism spectrum disorder (ASD) …

The powerful genome-wide association studies (GWAS) revealed common mutations that
increase susceptibility for schizophrenia (SZ) and bipolar disorder (BD), but the vast majority …

Objectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general
population. The relative contribution of genetic factors has been estimated to be up to 80 …

Purpose 'Big data'are accumulating in a multitude of domains and offer novel opportunities
for research. The role of these resources in mental health investigations remains relatively …