Basonuclin-2 regulates extracellular matrix production and degradation

A Orang, BK Dredge, CY Liu, JM Bracken… - Life science …, 2023 - life-science-alliance.org
Epithelial–mesenchymal transition is essential for tissue patterning and organization. It
involves both regulation of cell motility and alterations in the composition and organization of …

[HTML][HTML] Continuous inflammatory stimulation leads via metabolic plasticity to a prometastatic phenotype in triple-negative breast cancer cells

D Morein, L Rubinstein-Achiasaf, H Brayer, O Dorot… - Cells, 2021 - mdpi.com
Chronic inflammation promotes cancer progression by affecting the tumor cells and their
microenvironment. Here, we demonstrate that a continuous stimulation (~ 6 weeks) of triple …

[HTML][HTML] Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast …

T Baram, N Oren, N Erlichman, T Meshel… - Cancers, 2022 - mdpi.com
Simple Summary Immune checkpoint blockades (ICBs) to PD-L1 have led to major
breakthroughs in cancer therapy, but in triple-negative breast cancer (TNBC) success rates …

Chemokine systems in oncology: From microenvironment modulation to nanocarrier innovations

M Guan, S Liu, YG Yang, Y Song, Y Zhang… - International Journal of …, 2024 - Elsevier
Over the past few decades, significant strides have been made in understanding the pivotal
roles that chemokine networks play in tumor biology. These networks, comprising …

[HTML][HTML] CXCL2-mediated ATR/CHK1 signaling pathway and platinum resistance in epithelial ovarian cancer

S Nie, Y Wan, H Wang, J Liu, J Yang, R Sun… - Journal of ovarian …, 2021 - Springer
Tumor microenvironment and chemokines play a significant role in cancer chemoresistance.
This study was designed to reveal the important role of CXCL2 in platinum resistance in …

[HTML][HTML] Chemoattraction of neoplastic glial cells with CXCL10, CCL2 and CCL11 as a paradigm for a promising therapeutic approach for primary brain tumors

L Déry, G Charest, B Guérin, M Akbari… - International Journal of …, 2021 - mdpi.com
Chemoattraction is a normal and essential process, but it can also be involved in
tumorigenesis. This phenomenon plays a key role in glioblastoma (GBM). The GBM tumor …

[HTML][HTML] Ackr3-Venus knock-in mouse lights up brain vasculature

AT Ehrlich, M Semache, P Couvineau, S Wojcik… - Molecular brain, 2021 - Springer
The atypical chemokine receptor 3, ACKR3, is a G protein-coupled receptor, which does not
couple to G proteins but recruits βarrestins. At present, ACKR3 is considered a target for …

[HTML][HTML] Knockdown SENP1 Suppressed the Angiogenic Potential of Mesenchymal Stem Cells by Impacting CXCR4-Regulated MRTF-A SUMOylation and CCN1 …

R Zhang, Q Liu, C Lyu, X Gao, W Ma - Biomedicines, 2023 - mdpi.com
The angiogenic potential of mesenchymal stem cells (MSCs) is critical for adult vascular
regeneration and repair, which is regulated by various growth factors and cytokines. In the …

miR-31 促进骨髓间充质干细胞的增殖和迁移

张玉娟, 原一桐, 杜若琛, 田峰, 付媛, 王春芳 - 中国组织工程研究, 2023 - cjter.com
miR-31 促进骨髓间充质干细胞的增殖和迁移 Page 1 66|中国组织工程研究|第27卷|第1期|2023年
1月 中国组织工程研究 Chinese Journal of Tissue Engineering Research www.CJTER.com …

[HTML][HTML] MicroRNAs possibly involved in the development of bone metastasis in clear-cell renal cell carcinoma

L Kinget, E Roussel, D Lambrechts, B Boeckx… - Cancers, 2021 - mdpi.com
Bone metastasis in clear-cell renal cell carcinoma (ccRCC) leads to substantial morbidity
through skeletal related adverse events and implicates worse clinical outcomes. MicroRNAs …