The Mediterranean diet, plasma metabolome, and cardiovascular disease risk
Aims To investigate whether metabolic signature composed of multiple plasma metabolites
can be used to characterize adherence and metabolic response to the Mediterranean diet …
can be used to characterize adherence and metabolic response to the Mediterranean diet …
[PDF][PDF] Constrained maximum likelihood-based Mendelian randomization robust to both correlated and uncorrelated pleiotropic effects
With the increasing availability of large-scale GWAS summary data on various complex traits
and diseases, there have been tremendous interests in applications of Mendelian …
and diseases, there have been tremendous interests in applications of Mendelian …
The genetics of human ageing
The past two centuries have witnessed an unprecedented rise in human life expectancy.
Sustaining longer lives with reduced periods of disability will require an understanding of the …
Sustaining longer lives with reduced periods of disability will require an understanding of the …
[HTML][HTML] Deficiency of adenosine deaminase 2 (DADA2): updates on the phenotype, genetics, pathogenesis, and treatment
I Meyts, I Aksentijevich - Journal of clinical immunology, 2018 - Springer
Abstract Deficiency of ADA2 (DADA2) is the first molecularly described monogenic vasculitis
syndrome. DADA2 is caused by biallelic hypomorphic mutations in the ADA2 gene that …
syndrome. DADA2 is caused by biallelic hypomorphic mutations in the ADA2 gene that …
Molecular and cellular evolution of the primate dorsolateral prefrontal cortex
The granular dorsolateral prefrontal cortex (dlPFC) is an evolutionary specialization of
primates that is centrally involved in cognition. We assessed more than 600,000 single …
primates that is centrally involved in cognition. We assessed more than 600,000 single …
[HTML][HTML] Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study
Background Alcohol consumption and smoking, 2 major risk factors for cardiovascular
disease (CVD), often occur together. The objective of this study is to use a wide range of …
disease (CVD), often occur together. The objective of this study is to use a wide range of …
Associations of combined genetic and lifestyle risks with incident cardiovascular disease and diabetes in the UK Biobank Study
MA Said, N Verweij, P van der Harst - JAMA cardiology, 2018 - jamanetwork.com
Importance Genetic and lifestyle factors both contribute to the risk of developing
cardiovascular disease, but whether poor health behaviors are associated with similar …
cardiovascular disease, but whether poor health behaviors are associated with similar …
Heart disease and stroke statistics—2020 update: a report from the American Heart Association
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports on the most up-to-date statistics related to heart disease, stroke …
Health, annually reports on the most up-to-date statistics related to heart disease, stroke …
[HTML][HTML] Heart disease and stroke statistics-2021 update: a report from the American Heart Association.
Background The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
[HTML][HTML] Extrasynaptic NMDA receptors in acute and chronic excitotoxicity: implications for preventive treatments of ischemic stroke and late-onset Alzheimer's disease
SP Yu, MQ Jiang, SS Shim, S Pourkhodadad… - Molecular …, 2023 - Springer
Stroke and late-onset Alzheimer's disease (AD) are risk factors for each other; the
comorbidity of these brain disorders in aging individuals represents a significant challenge …
comorbidity of these brain disorders in aging individuals represents a significant challenge …