Background Post-stroke fatigue (PSF) is a significant and highly prevalent symptom, whose
mechanisms are poorly understood. The third Stroke Recovery and Rehabilitation …

Traumatic brain injury (TBI) is associated with chronic psychiatric complications and
increased risk for development of neurodegenerative pathology. Aged individuals account …

Traumatic brain injury (TBI) is a public health burden affecting millions of people. Sustained
neuroinflammation after TBI is often associated with poor outcome. As a result, increased …

Background There is a need for early therapeutic interventions after traumatic brain injury
(TBI) to prevent neurodegeneration. Microglia/macrophage (M/M) depletion and …

Mechanical impact-induced primary injury after traumatic brain injury (TBI) leads to acute
microglial pro-inflammatory activation and consequently mediates neurodegeneration …

Neuropsychiatric complications including depression and cognitive decline develop in the
years after traumatic brain injury (TBI), negatively affecting quality of life. Microglial and type …

The eight biological hallmarks of health that we initially postulated (Cell. 2021 Jan 7; 184 (1):
33-63) include features of spatial compartmentalization (integrity of barriers, containment of …

Traumatic brain injury (TBI) and stress are prevalent worldwide and can both result in life-
altering health problems. While stress often occurs in the absence of TBI, TBI inherently …

To investigate microglial mechanisms in central and peripheral inflammation after
experimental traumatic brain injury (TBI), we inhibited the colony-stimulating factor-1 …

Traumatic Brain Injury (TBI) is a prevalent form of neurological damage that may induce
varying degrees of cognitive dysfunction in patients, consequently impacting their quality of …