Research progress in the biological activities of 3, 4, 5-trimethoxycinnamic acid (TMCA) derivatives

Z Zhao, H Song, J Xie, T Liu, X Zhao, X Chen… - European journal of …, 2019 - Elsevier
Abstract TMCA (3, 4, 5-trimethoxycinnamic acid) ester and amide are privileged structural
scaffolds in drug discovery which are widely distributed in natural products and …

Identification of potential inhibitors of Schistosoma mansoni purine nucleoside phosphorylase from neolignan compounds using molecular modelling approaches

FJB Cardoso, LP Xavier, AV Santos… - Journal of …, 2022 - Taylor & Francis
Schistosomiasis is a parasitic disease that is part of the neglected tropical diseases (NTDs),
which cause significant levels of morbidity and mortality in millions of people throughout the …

[PDF][PDF] EVALUATION OF ANTIMALARIAL ACTIVITY OF 4-METHOXYBENZOYL NEOLIGNAN DERIVATIVES THROUGH A MOLECULAR DOCKING STUDY AGAINST …

S Triono, J Jumina, HD Pranowo… - Rasayan Journal of …, 2022 - rasayanjournal.co.in
In the present work, a molecular docking approach was conducted to investigate the
antimalarial activity of neolignan derivatives with 4-methoxybenzoyl substituent (N1-N10) …

Expression of cysteine proteinases and cystatins in parasites and use of cysteine proteinase inhibitors in parasitic diseases. Part III: Protozoa (2): Plasmodium spp.

S Abaza - Parasitologists United Journal, 2019 - puj.journals.ekb.eg
Genomic analysis of P. falciparum revealed more than thirty cysteine proteases (CPs).
However, the most studied CPs are four falcipains (FPs), three dipeptidyl peptidases, a …

[PDF][PDF] Atividade fitotóxica de di-hidrochalconas obtidas pela biorredução de chalconas promovidas pelo fungo endofítico Aspergillus flavus

FT Pinto, WS Ribeiro, MJC Corrêa… - Revista Virtual de …, 2020 - static.sites.sbq.org.br
The aim of this study was to evaluate the phytotoxic effects of dihydrochalcones obtained by
biotransformation reactions of the corresponding chalcones, promoted by the endophytic …

Molecular Docking Studies of (2E)-1 (1-Methyl-1H-Indol-3-yl)-3-Phenyl-Prop-2-en-one) as Antimalarial and Its Synthesis using Dimethylsulfate

K Mustikasari, JE Harap, TB Susilo - IOP Conference Series …, 2021 - iopscience.iop.org
Malaria is a disease with high prevalence in tropical and subtropical areas. The case of
parasite resistance to proguanil, an antimalarial drug, has prompted the discovery of new …