[HTML][HTML] A systematic literature review of leptospirosis outbreaks worldwide, 1970–2012

C Munoz-Zanzi, E Groene… - … de Salud Pública, 2020 - SciELO Public Health
Objective. This review describes the geographic and temporal distribution of, detection
methods for, and other epidemiological features of published leptospirosis outbreaks, with …

[HTML][HTML] Weil's Disease—Immunopathogenesis, Multiple Organ Failure, and Potential Role of Gut Microbiota

P Petakh, V Isevych, A Kamyshnyi, V Oksenych - Biomolecules, 2022 - mdpi.com
Leptospirosis is an important zoonotic disease, causing about 60,000 deaths annually. In
this review, we have described in detail the immunopathogenesis of leptospirosis, the …

Patient and family engagement in the ICU: report from the task force of the World Federation of Societies of Intensive and Critical Care Medicine

R Kleinpell, DK Heyland, J Lipman, CL Sprung… - Journal of critical …, 2018 - Elsevier
Purpose Patient and family engagement plays an important role in the intensive care unit
(ICU), however the degree to which practices are being implemented globally is not known …

[图书][B] Nelson's pediatric antimicrobial therapy

JS Bradley - 2012 - publications.aap.org
Welcome to the 29th edition of Nelson's Pediatric Antimicrobial Therapy, the third edition
written during the COVID-19 pandemic, which continues to significantly affect our lives and …

[HTML][HTML] Pathogenic Leptospira Evolved a Unique Gene Family Comprised of Ricin B-Like Lectin Domain-Containing Cytotoxins

R Chaurasia, AS Marroquin, JM Vinetz… - Frontiers in …, 2022 - frontiersin.org
Leptospirosis is a globally important neglected zoonotic disease. Previous data suggest that
a family of virulence-modifying (VM) proteins (PF07598) is a distinctive feature of group I …

Gut microbiota involved in leptospiral infections

X Xie, J Liu, X Chen, S Zhang, R Tang, X Wu… - The ISME …, 2022 - academic.oup.com
Leptospirosis is a re-emerging zoonotic disease worldwide. Intestinal bleeding is a common
but neglected symptom in severe leptospirosis. The regulatory mechanism of the gut …

[HTML][HTML] Neutralizing gut-derived lipopolysaccharide as a novel therapeutic strategy for severe leptospirosis

X Xie, X Chen, S Zhang, J Liu, W Zhang, Y Cao - Elife, 2024 - elifesciences.org
Leptospirosis is an emerging infectious disease caused by pathogenic Leptospira spp.
Humans and some mammals can develop severe forms of leptospirosis accompanied by a …

Acute kidney injury in leptospirosis: A country-level report

E Rista, E Puca, V Cadri, K Saliaj, I Akshija… - Travel Medicine and …, 2022 - Elsevier
1.1. Study design We conducted a prospective, observational, monocentric study in the span
of five years, from 2010 to 2015.119 consecutive patients admitted to the Department of …

Tropical diseases in the ICU: A syndromic approach to diagnosis and treatment

DR Karnad, GA Richards, GS Silva, P Amin - Journal of Critical Care, 2018 - Elsevier
Abstract Tropical infections form 20–30% of ICU admissions in tropical countries. Diarrheal
diseases, malaria, dengue, typhoid, rickettsial diseases and leptospirosis are common …

Severe leptospirosis in non-tropical areas: a nationwide, multicentre, retrospective study in French ICUs

AF Miailhe, E Mercier, A Maamar, JC Lacherade… - Intensive Care …, 2019 - Springer
Purpose To report the incidence, risk factors, clinical presentation, and outcome predictors of
severe leptospirosis requiring intensive care unit (ICU) admission in a temperate zone …