Gene co-expression network tools and databases for crop improvement

RA Zainal-Abidin, S Harun, V Vengatharajuloo… - Plants, 2022 - mdpi.com
Transcriptomics has significantly grown as a functional genomics tool for understanding the
expression of biological systems. The generated transcriptomics data can be utilised to …

Review on computer-assisted biosynthetic capacities elucidation to assess metabolic interactions and communication within microbial communities

M Zulfiqar, V Singh, C Steinbeck… - Critical Reviews in …, 2024 - Taylor & Francis
Microbial communities thrive through interactions and communication, which are
challenging to study as most microorganisms are not cultivable. To address this challenge …

Complex regulatory networks influence pluripotent cell state transitions in human iPSCs

TD Arthur, JP Nguyen, A D'Antonio-Chronowska… - Nature …, 2024 - nature.com
Stem cells exist in vitro in a spectrum of interconvertible pluripotent states. Analyzing
hundreds of hiPSCs derived from different individuals, we show the proportions of these …

Interaction between phenylpropane metabolism and oil accumulation in the developing seed of Brassica napus revealed by high temporal-resolution transcriptomes

L Yu, D Liu, F Yin, P Yu, S Lu, Y Zhang, H Zhao, C Lu… - BMC biology, 2023 - Springer
Background Brassica napus is an important oilseed crop providing high-quality vegetable
oils for human consumption and non-food applications. However, the regulation between …

hCoCena: horizontal integration and analysis of transcriptomics datasets

M Oestreich, L Holsten, S Agrawal, K Dahm… - …, 2022 - academic.oup.com
Motivation Transcriptome-based gene co-expression analysis has become a standard
procedure for structured and contextualized understanding and comparison of different …

Systematic elucidation of independently modulated genes in Lactiplantibacillus plantarum reveals a trade‐off between secondary and primary metabolism

S Qiu, Y Huang, S Liang, H Zeng… - Microbial …, 2024 - Wiley Online Library
Lactiplantibacillus plantarum is a probiotic bacterium widely used in food and health
industries, but its gene regulatory information is limited in existing databases, which …

Emerging landscape of molecular interaction networks: Opportunities, challenges and prospects

G Panditrao, R Bhowmick, C Meena, RR Sarkar - Journal of Biosciences, 2022 - Springer
Network biology finds application in interpreting molecular interaction networks and
providing insightful inferences using graph theoretical analysis of biological systems. The …

Recent advances in the genetics underlying wheat grain protein content and grain protein deviation in hexaploid wheat

C Paina, PL Gregersen - Plant Biology, 2023 - Wiley Online Library
Wheat is one of the most important global crops and selection for better performance has
been ongoing since ancient times. As a quantitative trait controlled by the interplay of …

[HTML][HTML] Intracellular spatial transcriptomic analysis toolkit (InSTAnT)

A Kumar, AW Schrader, AE Boroojeny… - Research …, 2023 - ncbi.nlm.nih.gov
Imaging-based spatial transcriptomics technologies such as MERFISH offer snapshots of
cellular processes in unprecedented detail, but new analytic tools are needed to realize their …

GCEN: An easy-to-use toolkit for gene co-expression network analysis and lncRNAs annotation

W Chen, J Li, S Huang, X Li, X Zhang, X Hu… - Current Issues in …, 2022 - mdpi.com
Gene co-expression network analysis has been widely used in gene function annotation,
especially for long noncoding RNAs (lncRNAs). However, there is a lack of effective cross …