The endoplasmic reticulum (ER) is a principal subcellular organelle responsible for protein
quality control in the secretory pathway, preventing protein misfolding and aggregation …

Diabetes is a metabolic disease characterized by hyperglycemia, which induces the
production of AGEs, ROS, inflammatory cytokines, and growth factors, leading to the …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic. Of particular interest …

The PI3K/AKT/mTOR signaling pathway may play crucial roles in the pathogenesis of
obesity and diabetes mellitus, as well as metabolic syndromes, which could also be risk …

Long noncoding RNAs (lncRNAs) are a group of noncoding RNAs with transcript lengths of>
200 nucleotides. Mounting evidence suggests that lncRNAs are closely associated with …

Heart failure with preserved ejection fraction (HFpEF) is the largest unmet clinical need in
cardiovascular medicine. Despite decades of research, the treatment option for HFpEF is still …

Abstract Ethnopharmacological relevance Qi-Ju-Di-Huang-Pill (QJDH pill) is a Chinese
decoction. Although it is commonly used to treat eye conditions, such as diabetic retinopathy …

Aims Mitochondria‐associated endoplasmic reticulum membranes (MAMs) serve as a
crucial bridge connecting the endoplasmic reticulum (ER) and mitochondria within cells …

Heart disease is one of the principal death reasons around the world and there is a growing
requirement to discover novel healing targets that have the potential to avert or manage …

Diabetic cardiomyopathy (DCM) represents a distinct myocardial disorder elicited by
diabetes mellitus, characterized by aberrations in myocardial function and structural …