Host-pathogen interactions are fundamental to our understanding of infectious diseases.
Protein glycosylation is one kind of common post-translational modification, forming …

Viruses, as obligate intracellular parasites, are the pathogens that have the most intimate
relationship with their host, and as such, their genomes have been shaped directly by …

Viruses interact with hundreds to thousands of proteins in mammals, yet adaptation against
viruses has only been studied in a few proteins specialized in antiviral defense. Whether …

Influenza A viruses are a major cause of mortality. Given the potential for future lethal
pandemics, effective drugs are needed for the treatment of severe influenza such as that …

The identification of human-virus protein-protein interactions (PPIs) is an essential and
challenging research topic, potentially providing a mechanistic understanding of viral …

As the first line of defence against pathogens, cells mount an innate immune response,
which varies widely from cell to cell. The response must be potent but carefully controlled to …

Virulence factors (VFs) are molecules that allow microbial pathogens to overcome host
defense mechanisms and cause disease in a host. It is critical to study VFs for better …

Background Representing biological networks as graphs is a powerful approach to reveal
underlying patterns, signatures, and critical components from high-throughput biomolecular …

Proteomic and lipidomic profiling was performed over a time course of acute hepatitis C
virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular …

This handbook provides an up-to-date compendium of fundamental computer science
topics, techniques, and applications. Along with updating and revising many of the existing …