Mendelian randomization for cardiovascular diseases: principles and applications

SC Larsson, AS Butterworth… - European heart journal, 2023 - academic.oup.com
Large-scale genome-wide association studies conducted over the last decade have
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …

Inter-organ crosstalk during development and progression of type 2 diabetes mellitus

G Xourafa, M Korbmacher, M Roden - Nature Reviews Endocrinology, 2024 - nature.com
Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …

[HTML][HTML] Relationship Between Lipoprotein (a), Renal Function Indicators, and Chronic Kidney Disease: Evidence From a Large Prospective Cohort Study

Y Liu, R Wang, S Li, C Zhang, GYH Lip… - JMIR public health …, 2024 - publichealth.jmir.org
Background Chronic kidney disease (CKD) poses a significant global public health
challenge. While lipoprotein (a)(Lp [a]) has been established as a significant factor in …

Metabolic dysfunction-associated steatotic liver disease: Recent turning points for its diagnosis and management

SA Polyzos, CS Mantzoros - Metabolism-Clinical and …, 2024 - metabolismjournal.com
In the meantime, while endorsing the definition and the criteria of MASLD, during the period
of transition from NAFLD to MASLD, researchers should not uncritically translate NAFLD to …

Measuring lipoprotein (a) for cardiovascular disease prevention–in whom and when?

PE Thomas, S Vedel-Krogh… - Current Opinion in …, 2024 - journals.lww.com
Elevated lipoprotein (a) is an independent causal risk factor for atherosclerotic
cardiovascular disease and aortic valve stenosis and measuring lipoprotein (a) once in all …

[HTML][HTML] Diet-Wide Association Study for the Incidence of Type 2 Diabetes Mellitus in Community-Dwelling Adults Using the UK Biobank Data

J Liu, X Shang, Y Chen, W Tang, M Yusufu, Z Chen… - Nutrients, 2023 - mdpi.com
This longitudinal study used diet-wide association studies (DWAS) to investigate the
association between diverse dietary food and nutrient intakes and the onset of type 2 …

[HTML][HTML] Lipoprotein (a) in patients with breast cancer after chemotherapy: exploring potential strategies for cardioprotection

Z Wang, J Li - Lipids in Health and Disease, 2023 - Springer
Developments in neoadjuvant and adjuvant chemotherapy (CHT) have led to an increase in
the number of breast cancer survivors. The determination of an appropriate follow-up for …

Low Concentration of Lipoprotein (a) is an Independent Predictor of Incident Type 2 Diabetes

W Liu, G Zhang, Z Nie, X Guan, T Sun… - Hormone and …, 2024 - thieme-connect.com
The aim of the study was to assess the association between lipoprotein (a)[Lp (a)]
concentration and incident type 2 diabetes. A meta-analysis of qualified studies on the …

Identification of Novel Genes Associated with Atrial Fibrillation and Development of Atrial Fibrillation Predictive Models by Incorporating Polygenic Risk Scores and …

SY Chen, YC Chen, TY Liu, KC Chang, SS Chang… - medRxiv, 2023 - medrxiv.org
BACKGROUND: Atrial fibrillation (AF) is the most common atrial arrhythmia and is
subcategorized into numerous clinical phenotypes. Previous studies demonstrated that early …

[PDF][PDF] Mendelian randomization for cardiovascular diseases: principles and applications

S Burgess - 2023 - dr2pp.oss.ns-svc.cn
Large-scale genome-wide association studies conducted over the last decade have
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …