[HTML][HTML] Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …

[HTML][HTML] COVID-19: immunopathology and its implications for therapy

X Cao - Nature reviews immunology, 2020 - nature.com
Severe coronavirus disease 2019 (COVID-19) is characterized by pneumonia, lymphopenia,
exhausted lymphocytes and a cytokine storm. Significant antibody production is observed; …

[HTML][HTML] An update on current therapeutic drugs treating COVID-19

R Wu, L Wang, HCD Kuo, A Shannar, R Peter… - Current pharmacology …, 2020 - Springer
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented …

Natural product-derived phytochemicals as potential agents against coronaviruses: A review

JS Mani, JB Johnson, JC Steel, DA Broszczak… - Virus research, 2020 - Elsevier
Coronaviruses are responsible for a growing economic, social and mortality burden, as the
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …

[HTML][HTML] Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

[HTML][HTML] Traditional Chinese medicine in COVID-19

M Lyu, G Fan, G Xiao, T Wang, D Xu, J Gao… - … Pharmaceutica Sinica B, 2021 - Elsevier
COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread across the globe, posing an enormous threat to public health and safety …

[HTML][HTML] Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice

AJ Pruijssers, AS George, A Schäfer, SR Leist… - Cell reports, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the novel viral disease COVID-19. With no approved therapies, this pandemic illustrates the …

Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19

H Xu, S Li, J Liu, J Cheng, L Kang… - Proceedings of the …, 2023 - National Acad Sciences
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern,
and effective antiviral reagents are urgently needed. Traditional Chinese medicine theory …

One year update on the COVID-19 pandemic: Where are we now?

SK Mishra, T Tripathi - Acta tropica, 2021 - Elsevier
We are living through an unprecedented crisis with the rapid spread of the new coronavirus
disease (COVID-19) worldwide within a short time. The timely availability of thousands of …