Angiogenesis is required in cancer, including gynecological cancers, for the growth of
primary tumors and secondary metastases. Development of anti-angiogenesis therapy in …

Simple Summary The potential effects of metformin in terms of cancer prevention and
therapy have been widely studied, and a number of studies have indicated its potential role …

BackgroundFor gynecological cancer patients, the beneficial effect of metformin use remains
controversial due to inconsistent results of published articles. By conducting a meta …

Background: Experiments have shown that metformin can inhibit cancer cell growth, but
clinical observations have been inconsistent, so we pooled the currently available data to …

Oncogenic types of human papillomaviruses (HPVs) are major human carcinogens. The
viral E6/E7 oncogenes maintain the malignant growth of HPV‐positive cancer cells …

Background The results of a meta-analysis of retrospective studies suggest that the use of
metformin in cancer patients may prolong progression-free disease survival and overall …

Several molecules are being investigated for their ability to enhance the anti-tumor effect of
radiotherapy. The widely prescribed antidiabetic drug metformin has been suggested to …

Insulin resistance and hyperinsulinemia play a key role in type 1 endometrial cancer
pathogenesis. Most of these cancers develop on a background of overweight or type 2 …

Simple Summary Recent studies have shown that metformin combined with clinical
chemotherapeutic drugs could cause decreased cell toxicity and attenuate tumor resistance …

Aims The role of metformin on the radiosensitising effect of cisplatin is not clear. Here we
investigated the radiosensitising effect of metformin alone and combined with cisplatin in …