Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Evidence from human cohorts indicates that chronic insomnia is associated with higher risk
of cardiometabolic diseases (CMD), yet whether gut microbiota plays a role is unclear. Here …

The prevalence of metabolic diseases, including obesity, dyslipidemia, type 2 diabetes
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …

Compositional oscillations of the gut microbiome are essential for normal peripheral
circadian rhythms, both of which are disrupted in diet-induced obesity (DIO). Although time …

Various lifestyle and environmental factors are known to influence sleep. Increasingly,
evidence points to a role for the microbiota in regulating brain and behaviour. This article …

Rationale: Dysbiotic gut microbiota (GM) and NLRP3 inflammasome are proarrhythmic
factors in atrial fibrillation (AF). Herein, whether short-chain fatty acid (SCFA) produced from …

Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and
entrain each other, and thus affect host health and immune-mediated diseases. Here, we …

Time-restricted eating (TRE) is a dietary intervention that limits food consumption to a
specific time window each day. The effect of TRE on body weight and physiological …

Probiotic oral delivery has crucial implications in biomedical engineering, but its oral
bioavailability remains unsatisfactory because of the limited survival and colonization of …