Without epithelial–mesenchymal transitions, in which polarized epithelial cells are converted
into motile cells, multicellular organisms would be incapable of getting past the blastula …

All ectodermal organs, eg hair, teeth, and many exocrine glands, originate from two adjacent
tissue layers: the epithelium and the mesenchyme. Similar sequential and reciprocal …

Abstract Characterization of the progression of cellular states during human embryogenesis
can provide insights into the origin of pediatric diseases. We examined the transcriptional …

Objective To investigate the relation between preterm birth (gestational age< 37 weeks) and
risk of CKD from childhood into mid-adulthood. Design National cohort study. Setting …

Current approaches to the development of regenerative therapies have been influenced by
our understanding of embryonic development, stem cell biology, and tissue engineering …

The mammalian kidney develops in three successive steps from the initial pronephros via
the mesonephros to the adult metanephros. Although the nephric lineage is specified during …

Here we report a new isolation method for mouse glomeruli. The method is fast and simple
and allows for the isolation of virtually all glomeruli present in the adult mouse kidney with …

The female reproductive tract receives the oocytes for fertilization, supports the development
of the fetus and provides the passage for birth. Although abnormalities of this organ system …

Schematic diagram of glypicans. GAG, glycosaminoglycan chains; GPI,
glycosylphosphatidylinositol anchor. tion between dally and decapentaplegic (dpp). dpp …

The murine Six gene family, homologous to Drosophila sine oculis (so) which encodes a
homeodomain transcription factor, is composed of six members (Six1-6). Among the six …