The diabetic cardiomyopathy: the contributing pathophysiological mechanisms

T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

Endothelial-to-mesenchymal transition: An underappreciated mediator of diabetic complications

E Wang, H Wang, S Chakrabarti - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetes and its complications represent a great burden on the global healthcare system.
Diabetic complications are fundamentally diseases of the vasculature, with endothelial cells …

Biomass-derived hierarchical porous ZnO microtubules for highly selective detection of ppb-level nitric oxide at low temperature

C Li, BY Song, Y Teng, XF Zhang, ZP Deng… - Sensors and Actuators B …, 2021 - Elsevier
Highly sensitive and selective detection of nitric oxide (NO) has recently attracted much
attention due to its environmental pollution and biological role. Herein, hierarchical porous …

Cardiometabolic risk factors associated with type 2 diabetes mellitus: a mechanistic insight

S Chakraborty, A Verma, R Garg… - Clinical Medicine …, 2023 - journals.sagepub.com
A complex metabolic condition referred to as Type 2 diabetes mellitus (T2DM) is
characterized by insulin resistance (IR) and decreased insulin production. Obesity …

Left ventricular hypertrophy in diabetic cardiomyopathy: a target for intervention

M Mohan, A Dihoum, IR Mordi, AM Choy… - Frontiers in …, 2021 - frontiersin.org
Heart failure is an important manifestation of diabetic heart disease. Before the development
of symptomatic heart failure, as much as 50% of patients with type 2 diabetes mellitus …

β-Hydroxybutyrate inhibits histone deacetylase 3 to promote claudin-5 generation and attenuate cardiac microvascular hyperpermeability in diabetes

B Li, Y Yu, K Liu, Y Zhang, Q Geng, F Zhang, Y Li, J Qi - Diabetologia, 2021 - Springer
Aims/hypothesis Microvascular endothelial hyperpermeability, mainly caused by claudin-5
deficiency, is the initial pathological change that occurs in diabetes-associated …

Molecular mechanisms and therapeutic implications of endothelial dysfunction in patients with heart failure

V Tsigkou, E Oikonomou, A Anastasiou… - International Journal of …, 2023 - mdpi.com
Heart failure is a complex medical syndrome that is attributed to a number of risk factors;
nevertheless, its clinical presentation is quite similar among the different etiologies. Heart …

Transcriptomic analysis suggested the involvement of impaired lipid droplet biogenesis in graphene oxide-induced cytotoxicity in human umbilical vein endothelial …

Y Luo, X Wang, Y Cao - Chemico-Biological Interactions, 2021 - Elsevier
Previous studies revealed that direct contact with graphene oxide (GO) induced cytotoxic
effects, but the importance of involvement of metabolic pathways, in particular lipid …

[HTML][HTML] Role of diabetes mellitus in heart failure with preserved ejection fraction: a review article

O Mgbemena, Y Zhang, G Velarde - Cureus, 2021 - ncbi.nlm.nih.gov
The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is complex
and poorly understood. There is a high prevalence of Diabetes Mellitus (DM) in patients with …

Incidence of depression in patients with cardiovascular disease and type 2 diabetes: a nationwide cohort study

B Zareini, KK Sørensen, P Blanche… - Clinical Research in …, 2023 - Springer
Background Estimating how type 2 diabetes (T2D) affects the rate of depression in
cardiovascular disease (CVD) can help identify high-risk patients. The aim is to investigate …