[HTML][HTML] Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review

Z Vinarov, M Abdallah, JAG Agundez… - European Journal of …, 2021 - Elsevier
The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

[HTML][HTML] Effects of psychological, environmental and physical stressors on the gut microbiota

JP Karl, AM Hatch, SM Arcidiacono… - Frontiers in …, 2018 - frontiersin.org
Stress, a ubiquitous part of daily human life, has varied biological effects which are
increasingly recognized as including modulation of commensal microorganisms residing in …

Systematic review: exercise‐induced gastrointestinal syndrome—implications for health and intestinal disease

RJS Costa, RMJ Snipe, CM Kitic… - Alimentary …, 2017 - Wiley Online Library
Background “Exercise‐induced gastrointestinal syndrome” refers to disturbances of
gastrointestinal integrity and function that are common features of strenuous exercise. Aim …

Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: impact on intestinal epithelial barrier, gut microbiota …

C Li, G Ai, Y Wang, Q Lu, C Luo, L Tan, G Lin… - Pharmacological …, 2020 - Elsevier
Abstract Berberine (BBR), a naturally-occurring isoquinoline alkaloid isolated from several
Chinese herbal medicines, has been widely used for the treatment of dysentery and colitis …

Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress

JP Karl, LM Margolis, EH Madslien… - American Journal …, 2017 - journals.physiology.org
The magnitude, temporal dynamics, and physiological effects of intestinal microbiome
responses to physiological stress are poorly characterized. This study used a systems …

Heat stress directly impairs gut integrity and recruits distinct immune cell populations into the bovine intestine

F Koch, U Thom, E Albrecht… - Proceedings of the …, 2019 - National Acad Sciences
High ambient temperature has multiple potential effects on the organism such as
hyperthermia, endotoxemia, and/or systemic inflammation. However, it is often difficult to …

A review of heat stress in chickens. Part I: Insights into physiology and gut health

G Brugaletta, JR Teyssier, SJ Rochell, S Dridi… - Frontiers in …, 2022 - frontiersin.org
Heat stress (HS) compromises the yield and quality of poultry products and endangers the
sustainability of the poultry industry. Despite being homeothermic, chickens, especially fast …

Effects of heat stress on the gut health of poultry

MH Rostagno - Journal of animal science, 2020 - academic.oup.com
Stress is a biological adaptive response to restore homeostasis, and occurs in every animal
production system, due to the multitude of stressors present in every farm. Heat stress is one …

Exercise and intestinal permeability: another form of exercise-induced hormesis?

BH Keirns, NA Koemel, CM Sciarrillo… - American Journal …, 2020 - journals.physiology.org
Regular aerobic exercise has numerous benefits on human physiology, arguably by serving
as a hormetic stressor resulting in positive adaptations over time. It has long been known …

Impact of heat stress on lactational performance of dairy cows

S Tao, RMO Rivas, TN Marins, YC Chen, J Gao… - Theriogenology, 2020 - Elsevier
Lactating dairy cows exhibit a myriad of responses to heat stress. These responses partially
facilitate the thermal balance between heat gain and heat loss, but also account for …