Abstract Wilms' tumor (WT), the most common childhood kidney cancer, develops in
association with an underlying germline predisposition in up to 15% of cases. Germline …

Objective To study the pregnancy rate after ulipristal acetate (UPA) therapy for fibroids.
Design Retrospective analysis of a series of 52 patients prospectively included in the …

Congenital anomalies of the kidney and urinary tract or “CAKUT” describes a spectrum of
developmental disorders with a range of associated clinical presentations and functional …

STUDY HYPOTHESIS Region-specific transcriptional profiling of tissues and cultured
epithelial cells from the human epididymis will predict functional specialization along the …

Podocytes are differentiated post-mitotic cells that cannot replace themselves after injury.
Glomerular parietal epithelial cells are proposed to be podocyte progenitors. To test whether …

Understanding of cellular transdifferentiation is limited by the technical inability to track
multiple lineages in vivo. To overcome this we developed a new tool to simultaneously fate …

Linoleic acid (LA), an n-6 polyunsaturated fatty acid (PUFA), is obtained from the maternal
diet during pregnancy, and is essential for normal fetal growth and development. A maternal …

The GDNF (Glial cell line-derived neurotrophic factor)/Ret/Akt signaling pathway is essential
to the development of ENS (enteric nervous system) as well as kidney. We previously …

Nephropathies arise from conditions that alter nephron development or trigger nephron
damage during neonatal, juvenile, and adult stages of life. Much evidence suggests that a …

A special feature of the renal stem/progenitor cell niche is its always close neighborhood to
the capsule during organ development. To explore this link, neonatal kidney was …