This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

A-type voltage-gated potassium (Kv) channels are major regulators of neuronal excitability
that have been mainly characterized in the central nervous system. By contrast, there is a …

This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …

Spinal cord injury (SCI) causes maladaptive changes to nociceptive synaptic circuits within
the injured spinal cord. Changes also occur at remote regions including the brain stem …

Key points There is clinical evidence showing that prostatic inflammation contributes to
overactive bladder symptoms in male patients; however, little is known about the underlying …

Aims To investigate the role of nerve growth factor (NGF) in lower urinary tract dysfunction in
mice with spinal cord injury (SCI). Methods Using 4‐week SCI mice, single‐filling cystometry …

First-order somatosensory neurons transduce and convey information about the external or
internal environment of the body to the central nervous system. They are pseudo unipolar …

Overactive bladder (OAB) is a common debilitating condition characterized by urgency
symptoms with detrimental effects on the quality of life and survival. The exact etiology of …

We examined bladder and urethral sphincter activity in mice with or without spinal cord
injury (SCI) after C-fiber afferent desensitization induced by capsaicin pretreatment and …

This article summarizes anatomical, neurophysiological, and pharmacological studies in
humans and animals to provide insights into the neural circuitry and neurotransmitter …