[HTML][HTML] T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
[HTML][HTML] Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?
The rapid development of multiple vaccines providing strong protection from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
highlighted the need for vaccines that not only prevent disease but also prevent …
highlighted the need for vaccines that not only prevent disease but also prevent …
[HTML][HTML] Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
B Boras, RM Jones, BJ Anson, D Arenson… - Nature …, 2021 - nature.com
COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …
SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …
[HTML][HTML] Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2
Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with
antigenic changes in the spike protein are neutralized less efficiently by serum antibodies …
antigenic changes in the spike protein are neutralized less efficiently by serum antibodies …
[HTML][HTML] Activation or exhaustion of CD8+ T cells in patients with COVID-19
In addition to CD4+ T cells and neutralizing antibodies, CD8+ T cells contribute to protective
immune responses against SARS-CoV-2 in patients with coronavirus disease 2019 (COVID …
immune responses against SARS-CoV-2 in patients with coronavirus disease 2019 (COVID …
[HTML][HTML] Count on us: T cells in SARS-CoV-2 infection and vaccination
K Kedzierska, PG Thomas - Cell Reports Medicine, 2022 - cell.com
Robust T cell responses have been associated with milder outcomes in many infections. T
cells also establish long-term memory pools and, as they are predominantly directed toward …
cells also establish long-term memory pools and, as they are predominantly directed toward …
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion
V Fumagalli, M Ravà, D Marotta, P Di Lucia… - Science …, 2021 - science.org
The development of a tractable small animal model faithfully reproducing human
coronavirus disease 2019 pathogenesis would arguably meet a pressing need in …
coronavirus disease 2019 pathogenesis would arguably meet a pressing need in …
Exposure to lung-migrating helminth protects against murine SARS-CoV-2 infection through macrophage-dependent T cell activation
OO Oyesola, KL Hilligan, S Namasivayam… - Science …, 2023 - science.org
Helminth endemic regions report lower COVID-19 morbidity and mortality. Here, we show
that lung remodeling from a prior infection with a lung-migrating helminth, Nippostrongylus …
that lung remodeling from a prior infection with a lung-migrating helminth, Nippostrongylus …