[HTML][HTML] Synthetic methodologies and therapeutic potential of indole-3-carbinol (I3C) and its derivatives
F Centofanti, A Buono, M Verboni, C Tomino… - Pharmaceuticals, 2023 - mdpi.com
Indole-3-carbinol (I3C) is a natural product contained in vegetables belonging to the
Brassicaceae family and has been studied in recent decades for its biological and …
Brassicaceae family and has been studied in recent decades for its biological and …
[HTML][HTML] The breadth of bacteriophages contributing to the development of the phage-based vaccines for COVID-19: An ideal platform to design the multiplex vaccine
Phages are highly ubiquitous biological agents, which means they are ideal tools for
molecular biology and recombinant DNA technology. The development of a phage display …
molecular biology and recombinant DNA technology. The development of a phage display …
[HTML][HTML] Identification of natural lead compounds against hemagglutinin-esterase surface glycoprotein in human coronaviruses investigated via MD simulation …
The pandemic outbreak of human coronavirus is a global health concern that affects people
of all ages and genders, but there is currently still no effective, approved and potential drug …
of all ages and genders, but there is currently still no effective, approved and potential drug …
[HTML][HTML] Molecular Understanding of ACE-2 and HLA-conferred differential susceptibility to COVID-19: host-directed insights opening new windows in COVID-19 …
The genetic variants of HLAs (human leukocyte antigens) play a crucial role in the virus–
host interaction and pathology of COVID-19. The genetic variants of HLAs not only influence …
host interaction and pathology of COVID-19. The genetic variants of HLAs not only influence …
[HTML][HTML] Luteolin Isolated from Juncus acutus L., a Potential Remedy for Human Coronavirus 229E
A Hakem, L Desmarets, R Sahli, RB Malek, C Camuzet… - Molecules, 2023 - mdpi.com
The COVID-19 pandemic, caused by SARS-CoV-2, addressed the lack of specific antiviral
drugs against coronaviruses. In this study, bioguided fractionation performed on both ethyl …
drugs against coronaviruses. In this study, bioguided fractionation performed on both ethyl …
GINCM-DTA: A graph isomorphic network with protein contact map representation for potential use against Covid-19 and omicron subvariants bq. 1, bq. 1.1, xbb. 1.5 …
The COVID-19 pandemic's profound impact on global health and the economy underscores
the need for new computational strategies to rapidly identify potential antiviral drugs against …
the need for new computational strategies to rapidly identify potential antiviral drugs against …
[HTML][HTML] Exploration of potent antiviral phytomedicines from lauraceae family plants against SARS-CoV-2 main protease
A new Coronaviridae strain, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-
CoV-2), emerged from Wuhan city of China and caused one of the substantial global health …
CoV-2), emerged from Wuhan city of China and caused one of the substantial global health …
[HTML][HTML] In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease
I Mostafa, NH Mohamed, B Mohamed, R Almeer… - … Science and Pollution …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a rapidly growing pandemic that requires
urgent therapeutic intervention. Finding potential anti COVID-19 drugs aside from approved …
urgent therapeutic intervention. Finding potential anti COVID-19 drugs aside from approved …
Revolutionizing Treatment Strategies for Autoimmune and Inflammatory Disorders: The Impact of Dipeptidyl-Peptidase 4 Inhibitors
Abstract DPP4 (Dipeptidyl-peptidase 4) a versatile protease, emerges as a prominent player
in soluble and membrane-bound forms. Its heightened expression has been intimately …
in soluble and membrane-bound forms. Its heightened expression has been intimately …
[HTML][HTML] An efflux pump in genomic island GI-M202a mediates the transfer of polymyxin B resistance in Pandoraea pnomenusa M202
W Gao, C Li, F Wang, Y Yang, L Zhang, Z Wang… - International …, 2024 - Springer
Background Polymyxin B is considered a last-line therapeutic option against multidrug-
resistant gram-negative bacteria, especially in COVID-19 coinfections or other serious …
resistant gram-negative bacteria, especially in COVID-19 coinfections or other serious …