Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

High mobility group box 1 (HMGB1) is a nonhistone nuclear protein that has multiple
functions according to its subcellular location. In the nucleus, HMGB1 is a DNA chaperone …

The research field of ferroptosis has seen exponential growth over the past few years, since
the term was coined in 2012. This unique modality of cell death, driven by iron-dependent …

Maintaining the balance of a cell's redox function is key to determining cell fate. In the critical
redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent …

Osteoarthritis (OA) is a degenerative joint disease characterized by low-grade inflammation
and high levels of clinical heterogeneity. Aberrant chondrocyte metabolism is a response to …

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Mitochondria are known to generate approximately 90% of cellular reactive oxygen species
(ROS). The imbalance between mitochondrial reactive oxygen species (mtROS) production …

The review presents modern views about the role of oxidative stress reactions in the
pathogenesis of types 1 and 2 diabetes mellitus and their complications based on the …