Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …

Abstract Objectives One-fifth of Covid-19 patients suffer a severe course of Covid-19
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …

Cytokine release syndrome (CRS) is a major cause of the multi-organ injury and fatal
outcome induced by SARS-CoV-2 infection in severe COVID-19 patients. Metabolism can …

Recent advances in the pathophysiologic understanding of coronavirus disease 2019
(COVID-19) suggests that cytokine release syndrome (CRS) has an association with the …

Introduction Hospitalised patients with coronavirus disease 2019 (COVID-19) as a result of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have a high …

Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by
cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway …

Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …

The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …

Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …