The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …
Small molecules in the treatment of COVID-19
S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
The role of oxidative stress in the pathogenesis of infections with coronaviruses
Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …
organs such as the central nervous system, the lung and the heart. The coronavirus disease …
Targeting SARS-CoV-2 papain-like protease in the postvaccine era
While vaccines remain at the forefront of global healthcare responses, pioneering
therapeutics against SARS-CoV-2 are expected to fill the gaps for waning immunity. Rapid …
therapeutics against SARS-CoV-2 are expected to fill the gaps for waning immunity. Rapid …
SARS-CoV-2 non-structural proteins and their roles in host immune evasion
Coronavirus disease 2019 (COVID-19) has caused an unprecedented global crisis and
continues to threaten public health. The etiological agent of this devastating pandemic …
continues to threaten public health. The etiological agent of this devastating pandemic …
Protein post-translational modification in SARS-CoV-2 and host interaction
N Cheng, M Liu, W Li, BY Sun, D Liu, G Wang… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 can cause lung diseases, such as pneumonia and acute respiratory distress
syndrome, and multi-system dysfunction. Post-translational modifications (PTMs) related to …
syndrome, and multi-system dysfunction. Post-translational modifications (PTMs) related to …
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication
Y Miyamoto, Y Itoh, T Suzuki, T Tanaka, Y Sakai… - Communications …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORF6 is an antagonist of
interferon (IFN)-mediated antiviral signaling, achieved through the prevention of STAT1 …
interferon (IFN)-mediated antiviral signaling, achieved through the prevention of STAT1 …
Inflammatory pathways in COVID‐19: mechanism and therapeutic interventions
Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …
COVID-19 Biogenesis and Intracellular Transport
AA Mironov, MA Savin, GV Beznoussenko - International journal of …, 2023 - mdpi.com
SARS-CoV-2 is responsible for the COVID-19 pandemic. The structure of SARS-CoV-2 and
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …