CellAnn: a comprehensive, super-fast, and user-friendly single-cell annotation web server

P Lyu, Y Zhai, T Li, J Qian - Bioinformatics, 2023 - academic.oup.com
Motivation Single-cell sequencing technology has become a routine in studying many
biological problems. A core step of analyzing single-cell data is the assignment of cell …

Single-cell and bulk RNA sequencing reveal malignant epithelial cell heterogeneity and prognosis signatures in gastric carcinoma

Z Huang, C Wu, X Liu, S Lu, L You, F Guo, A Stalin… - Cells, 2022 - mdpi.com
Gastric carcinoma (GC) heterogeneity represents a major barrier to accurate diagnosis and
treatment. Here, we established a comprehensive single-cell transcriptional atlas to identify …

Investigate the stemness of adult adipose‐derived stromal cells based on single‐cell RNA‐sequencing

Q Liu, P Zhang, X Yuan, O Ya, Q Li, J Li… - Cell Biology …, 2022 - Wiley Online Library
The cellular heterogeneity and genetic features of stemness of adipose‐derived stromal
cells (ADSCs) remain unclear. Using single‐cell RNA sequencing (scRNA‐seq), we …

Unveiling the functional heterogeneity of cytokine-primed human umbilical cord mesenchymal stem cells through single-cell RNA sequencing

Z Hu, D Li, S Wu, K Pei, Z Fu, Y Yang, Y Huang… - Cell & Bioscience, 2024 - Springer
Abstract Background Mesenchymal stem cells (MSCs) hold immense promise for use in
immunomodulation and regenerative medicine. However, their inherent heterogeneity …

Telomere heterogeneity linked to metabolism and pluripotency state revealed by simultaneous analysis of telomere length and RNA-seq in the same human …

H Wang, K Zhang, Y Liu, Y Fu, S Gao, P Gong, H Wang… - BMC biology, 2017 - Springer
Background Telomere length heterogeneity has been detected in various cell types,
including stem cells and cancer cells. Cell heterogeneity in pluripotent stem cells, such as …

Single-cell sequencing in the field of stem cells

T Chen, J Li, Y Jia, J Wang, R Sang, Y Zhang… - Current …, 2020 - ingentaconnect.com
Variation and heterogeneity between cells are the basic characteristics of stem cells.
Traditional sequencing analysis methods often cover up this difference. Single-cell …

[HTML][HTML] Recent advances of single-cell RNA sequencing technology in mesenchymal stem cell research

G Zheng, ZY Xie, P Wang, YF Wu… - World Journal of Stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are multipotent stromal cells with great potential for clinical
applications. However, little is known about their cell heterogeneity at a single-cell …

Single-cell analysis defines the lineage plasticity of stem cells in cervix epithelium

Z Zhao, Y Wang, Y Wu, D Li, T Zhang, Y Ma, X Teng… - Cell Regeneration, 2021 - Springer
Abstract Information about the dynamic change and post-injury regeneration of cervical
epithelium is relatively rare, even though it is tightly related to gynecologic malignancy …

Single cell transcriptome sequencing: A new approach for the study of mammalian sex determination

I Stévant, S Nef - Molecular and cellular endocrinology, 2018 - Elsevier
Mammalian sex determination is a highly complex developmental process that is particularly
difficult to study due to the limited number of gonadal cells present at the bipotential stage …

[HTML][HTML] Recent advances in lineage differentiation from stem cells: hurdles and opportunities?

J Terryn, T Tricot, M Gajjar, C Verfaillie - F1000Research, 2018 - ncbi.nlm.nih.gov
Pluripotent stem cells have the property of long-term self-renewal and the potential to give
rise to descendants of the three germ layers and hence all mature cells in the human body …