[HTML][HTML] The SARS-CoV-2 spike glycoprotein biosynthesis, structure, function, and antigenicity: implications for the design of spike-based vaccine immunogens

L Duan, Q Zheng, H Zhang, Y Niu, Y Lou… - Frontiers in …, 2020 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public …

[HTML][HTML] COVID-19: characteristics and therapeutics

R Chilamakuri, S Agarwal - Cells, 2021 - mdpi.com
Novel coronavirus (COVID-19 or 2019-nCoV or SARS-CoV-2), which suddenly emerged in
December 2019 is still haunting the entire human race and has affected not only the …

[HTML][HTML] SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

KS Corbett, DK Edwards, SR Leist, OM Abiona… - Nature, 2020 - nature.com
A vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is needed to
control the coronavirus disease 2019 (COVID-19) global pandemic. Structural studies have …

[HTML][HTML] The use of medicinal plants to prevent COVID-19 in Nepal

D Khadka, MK Dhamala, F Li, PC Aryal… - Journal of ethnobiology …, 2021 - Springer
Background Medicinal plants are the fundamental unit of traditional medicine system in
Nepal. Nepalese people are rich in traditional medicine especially in folk medicine …

[HTML][HTML] The global prevalence of depression, anxiety, stress, and, insomnia and its changes among health professionals during COVID-19 pandemic: A rapid …

S Mahmud, S Hossain, A Muyeed, MM Islam, M Mohsin - Heliyon, 2021 - cell.com
Background During the COVID-19 pandemic, the health professionals who are at the
frontline of this crisis have been facing extreme psychological disorders. This research aims …

SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders

N Amruta, WH Chastain, M Paz, RJ Solch… - Cytokine & growth factor …, 2021 - Elsevier
SARS-CoV-2 is a novel coronavirus that severely affects the respiratory system, is the cause
of the COVID-19 pandemic, and is projected to result in the deaths of 2 million people …

[HTML][HTML] COVID-19 vaccine hesitancy among Ethiopian healthcare workers

R Mohammed, TM Nguse, BM Habte, AM Fentie… - PloS one, 2021 - journals.plos.org
Introduction COVID-19 poses significant health and economic threat prompting international
firms to rapidly develop vaccines and secure quick regulatory approval. Although COVID-19 …

SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4

F Onodi, L Bonnet-Madin, L Meertens, L Karpf… - Journal of Experimental …, 2021 - rupress.org
Several studies have analyzed antiviral immune pathways in late-stage severe COVID-19.
However, the initial steps of SARS-CoV-2 antiviral immunity are poorly understood. Here we …

High-resolution structures of the SARS-CoV-2 2′-O-methyltransferase reveal strategies for structure-based inhibitor design

M Rosas-Lemus, G Minasov, L Shuvalova, NL Inniss… - Science …, 2020 - science.org
There are currently no antiviral therapies specific for SARS-CoV-2, the virus responsible for
the global pandemic disease COVID-19. To facilitate structure-based drug design, we …

[HTML][HTML] COVID-19-associated school closures and related efforts to sustain education and subsidized meal programs, United States, February 18–June 30, 2020

N Zviedrite, JD Hodis, F Jahan, H Gao, A Uzicanin - PloS one, 2021 - journals.plos.org
Pre-emptive school closures are frontline community mitigation measures recommended by
the US Centers for Disease Control and Prevention (CDC) for implementation during severe …