Pyridines and Imidazopyridines with medicinal significance

T LS Kishbaugh - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
Pyridine and pyridine-fused ring systems are ubiquitous in medicinal research and
demonstrate such diverse pharmacological benefits as anticonvulsant therapies, treatment …

[HTML][HTML] Pharmacological Potential and Synthetic Approaches of Imidazo[4,5-b]pyridine and Imidazo[4,5-c]pyridine Derivatives

M Krause, H Foks, K Gobis - Molecules, 2017 - mdpi.com
The structural resemblance between the fused imidazopyridine heterocyclic ring system and
purines has prompted biological investigations to assess their potential therapeutic …

Novel amino substituted tetracyclic imidazo [4, 5-b] pyridine derivatives: Design, synthesis, antiproliferative activity and DNA/RNA binding study

B Lončar, N Perin, M Mioč, I Boček, L Grgić… - European journal of …, 2021 - Elsevier
A novel series of tetracyclic imidazo [4, 5-b] pyridine derivatives was designed and
synthesized as potential antiproliferative agents. Their antiproliferative activity against …

[HTML][HTML] Synthesis of coumarins linked with 1, 2, 3-triazoles under microwave irradiation and evaluation of their antimicrobial and antioxidant activity

M Nibin Joy, YD Bodke, S Telkar… - Journal of the Mexican …, 2020 - scielo.org.mx
A series of coumarin derivatives linked with 1, 2, 3-triazoles has been synthesized by
utilizing the copper catalyzed azide-alkyne cycloaddition reaction and were screened for …

Two-photon brightness of highly fluorescent imidazopyridine derivatives: Two-photon and ultrafast transient absorption studies

LHZ Cocca, A Pelosi, LF Sciuti, LMG Abegao… - Journal of Molecular …, 2022 - Elsevier
Imidazopyridine derivatives are unnatural purines isosteres and have been idealized and
synthesized in the last decades, given their great applicability in several science areas. For …

Design, synthesis, and biological evaluation of imidazopyridine‐linked thiazolidinone as potential anticancer agents

MA Iqbal, A Husain, O Alam, SA Khan… - Archiv der …, 2020 - Wiley Online Library
In this study, two series of imidazopyridine‐linked thiazolidinone rings (5a–h and 6a–h)
constituting 16 new compounds were synthesized and tested for their antiproliferative …

Novel tacrine derivatives exhibiting improved acetylcholinesterase inhibition: Design, synthesis and biological evaluation

EK Reddy, C Remya, K Mantosh, AM Sajith… - European journal of …, 2017 - Elsevier
A novel series of twenty four tacrine derivatives were designed and synthesised. Among
these, thirteen were taken for the acetylcholinesterase (AChE) inhibition studies. Three …

Functionalised dihydroazo pyrimidine derivatives from Morita–Baylis–Hillman acetates: synthesis and studies against acetylcholinesterase as its inhibitors

EK Reddy, C Remya, AM Sajith, KV Dileep… - RSC …, 2016 - pubs.rsc.org
A wide array of dihydro [1, 5] azo [1, 2-a] pyrimidine 2-esters have been synthesised at room
temperature in moderate to good yields through one-pot reaction between nitrostyrene …

Separation of ephedrine and pseudoephedrine enantiomers using a polysaccharide‐based chiral column: a normal phase liquid chromatography–high‐resolution …

AK Karakka Kal, TK Karatt, R Sayed, M Philip… - Chirality, 2019 - Wiley Online Library
Chiral considerations are found to be very much relevant in various aspects of forensic
toxicology and pharmacology. In forensics, it has become increasingly important to identify …

Microwave-assisted synthesis of certain pyrrolylpyridines, some derived ring systems and their evaluation as anticancer and antioxidant agents

SAF Rostom, AA Bekhit - European Journal of Medicinal Chemistry, 2015 - Elsevier
The synthesis of 18 novel pyrrolylpyridines and some derived bi-, tri-and tetracyclic ring
systems using both the conventional heating and MW irradiation techniques is described …