Background There is considerable uncertainty regarding the optimal haemoglobin threshold
for the use of red blood cell (RBC) transfusions in anaemic patients. Blood is a scarce …

Despite numerous guidelines on the management of anaemia in surgical patients, there is
no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in …

The management of perioperative bleeding involves multiple assessments and strategies to
ensure appropriate patient care. Initially, it is important to identify those patients with an …

Importance More than 100 million units of blood are collected worldwide each year, yet the
indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to …

Importance Red blood cell transfusion is a common medical intervention with benefits and
harms. Objective To provide recommendations for use of red blood cell transfusion in adults …

Objective To compare patient outcomes of restrictive versus liberal blood transfusion
strategies in patients with cardiovascular disease not undergoing cardiac surgery. Design …

Objective To develop evidence-based clinical practice recommendations regarding
transfusion practices in non-bleeding, critically ill adults. Design A task force involving 13 …

Background Several new trials evaluating transfusion strategies in patients with
cardiovascular disease have recently been published, increasing the number of enrolled …

Anemia in cancer patients is quite common, with remarkable negative impacts on quality of
life and overall prognosis. The pathogenesis is complex and typically multifactorial, with iron …

Over the coming years, accelerating progress against cancer will be associated with an
increased number of patients who require life-sustaining therapies for infectious or toxic …