Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

F Kronenberg, S Mora, ESG Stroes… - European heart …, 2022 - academic.oup.com
Abstract This 2022 European Atherosclerosis Society lipoprotein (a)[Lp (a)] consensus
statement updates evidence for the role of Lp (a) in atherosclerotic cardiovascular disease …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

[HTML][HTML] PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021

M Banach, P Burchardt, K Chlebus… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

Effect of pelacarsen on lipoprotein (a) cholesterol and corrected low-density lipoprotein cholesterol

C Yeang, E Karwatowska-Prokopczuk, F Su… - Journal of the American …, 2022 - jacc.org
Background Laboratory methods that report low-density lipoprotein cholesterol (LDL-C)
include both LDL-C and lipoprotein (a) cholesterol [Lp (a)-C] content. Objectives The …

Lower extremity peripheral artery disease without chronic limb-threatening ischemia: a review

TS Polonsky, MM McDermott - Jama, 2021 - jamanetwork.com
Importance Lower extremity peripheral artery disease (PAD) affects approximately 8.5
million people in the US and approximately 230 million worldwide. Observations Peripheral …

[HTML][HTML] World heart federation cholesterol roadmap 2022

KK Ray, BA Ference, T Séverin, D Blom, SJ Nicholls… - Global …, 2022 - ncbi.nlm.nih.gov
Background: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial
infarction, stroke and peripheral arterial disease continue to be major causes of premature …

Aspirin for primary prevention of cardiovascular events in relation to lipoprotein (a) genotypes

P Lacaze, A Bakshi, M Riaz, G Polekhina… - Journal of the American …, 2022 - jacc.org
Background The role of aspirin in reducing lipoprotein (a)-mediated atherothrombotic events
in primary prevention is not established. Objectives This study sought to assess whether low …

Novel and future lipid-modulating therapies for the prevention of cardiovascular disease

J Brandts, KK Ray - Nature Reviews Cardiology, 2023 - nature.com
Lowering the levels of LDL cholesterol in the plasma has been shown to reduce the risk of
atherosclerotic cardiovascular disease (ASCVD). Several other lipoproteins, such as …

Emerging RNA Therapeutics to Lower Blood Levels of Lp(a) JACC Focus Seminar 2/4

S Tsimikas, PM Moriarty, ES Stroes - Journal of the American College of …, 2021 - jacc.org
Abstract Lipoprotein (a)[Lp (a)] has risen to the level of an accepted cardiovascular disease
risk factor, but final proof of causality awaits a randomized trial of Lp (a) lowering. Inhibiting …

Lipoprotein (a) and benefit of PCSK9 inhibition in patients with nominally controlled LDL cholesterol

GG Schwartz, M Szarek, VA Bittner, R Diaz… - Journal of the American …, 2021 - jacc.org
Background Guidelines recommend nonstatin lipid-lowering agents in patients at very high
risk for major adverse cardiovascular events (MACE) if low-density lipoprotein cholesterol …